Deep Breathing Combined With Core Stability Exercises in the Treatment of Patients With Ankylosing Spondylitis

NCT07262294 | Recruiting

• 1 other identifier: Physical Therapy, Beni-Suef.
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

Exercise may be considered the gold standard for the management of mechanical and functional symptoms associated with patients having AS and they are considered as a safe and effective treatment for improving strength, spinal mobility, and physical fitness in general. However, there were no definite types or doses recommended over others. Additionally, poor posture is one of the consequences of AS due to pain, loss of flexibility, and muscular weakness which may also affect respiratory function. This faulty mechanical posture of the thoracic and cervical spine may affect the pulmonary function of these patients. Therefore, the purpose of the current study is to investigate the efficacy of deep breathing exercises added to core stability exercises in the treatment of patients suffering from AS.

Conditions

Ankylosing Spondylitis (AS)

Outcome Measures

Primary Outcomes (1)

• Respiratory function

  Forced vital capacity (FVC) which measure lung volume, and it reflects the capacity of the lung. Forced expiratory volume in 1 second (FEV1) which measure lung velocity, and it evaluate the presence of airway obstruction. FEV1/FVC it the index that differentiate between obstructive and restrictive lung disease.

  Patients will be examined after 4 to 6 weeks

Secondary Outcomes (1)

• Functional exercise capacity

  Patients will be examined after 4 to 6 weeks

Study Arms (2)

Deep Breathing exercise plus Core stability exercises

EXPERIMENTAL

Deep Breathing exercise is a type of exercise that engage the diaphragm to enhance the respiratory function, improve lung efficiency, and induce relaxation which improve the overall health condition.

Other: Exercises

Core Stability Exercises

ACTIVE COMPARATOR

Core Stability exercises are group of exercises designed to strengthen abdominal, back, lower limbs, and pelvis muscles which enhance posture and provide stability and body control during daily activities

Other: Exercises

Interventions

Exercises OTHER

Exercises

Core Stability Exercises; Deep Breathing exercise plus Core stability exercises

Eligibility Criteria

• Age: 25 Years - 45 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Receiving the same medical treatment
• Age range between 20 and 45 years
• Includes both male and female patients
• Diagnosed with stable ankylosing spondylitis (AS) for at least 3 months
• Not engaged in any other rehabilitation programs within the last 6 months

You may not qualify if:

• Presence of other systemic or neurological disorders
• Any change in medication within the last 6 months

Sponsors & Collaborators

• Beni-Suef University: lead

Study Sites (1)

Beni Suef University Hospital

Banī Suwayf, Egypt

RECRUITING

MeSH Terms

Conditions

Spondylitis, Ankylosing

Interventions

Exercise

Condition Hierarchy (Ancestors)

Axial Spondyloarthritis; Spondylarthropathies; Spondylarthritis; Spondylitis; Spinal Diseases; Bone Diseases; Musculoskeletal Diseases; Ankylosis; Joint Diseases; Arthritis

Intervention Hierarchy (Ancestors)

Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Masking Details: Double blind
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Lecturer of Orthopaedic Physical Therapy

Model Details: Parallel Assignment

Study Record Dates

• First Submitted: November 15, 2025
• First Posted: December 3, 2025
• Study Start: February 1, 2026
• Primary Completion (Estimated): November 30, 2026
• Study Completion (Estimated): December 30, 2026
• Last Updated: March 9, 2026

Record last verified: 2025-11

Locations

EG (1)