Choroidal Venous Congestion Following Scleral Buckling - An Imaging Study

NCT07260097 | Recruiting DMC

• 1 other identifier: 2025-0251
• Study Type: observational
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to understand how blood flow at the back of the eye changes over time after this surgery. By studying these changes, the investigators hope to gain insights that could help improve the understanding of other eye diseases, such as age-related macular degeneration (AMD) and polypoidal choroidal vasculopathy(PCV). This research may contribute to better treatments and outcomes for future patients.

Conditions

Pachychoroid Disease

Outcome Measures

Primary Outcomes (1)

• Post operative choroidal venous congestion

  Proportion of eyes demonstrating progression in choroidal venous congestion at 1 year, defined by increased choroidal thickness, increase in number of quadrants with pachyvessels, or new vortex vein anastomosis on multimodal imaging.

  1 year

Eligibility Criteria

• Age: 21 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

50 participants from the Singapore National Eye Centre.

You may qualify if:

• Age 21 years and above
• Ability to provide informed consent
• First occurrence of a retinal detachment in one eye, deemed to require SB surgery with or without vitrectomy and/or cataract surgery.
• Clinically normal fellow eye (no previous intraocular surgery except for cataract extraction with lens implant, intraocular laser or injection procedures).

You may not qualify if:

• Affected eye undergoing vitreoretinal procedure other than an SB surgery with or without vitrectomy and/or cataract surgery.
• Pregnant or nursing women
• Persons who are unable to give informed consent

Sponsors & Collaborators

• Singapore National Eye Centre: lead

Study Sites (1)

Singapore Eye Research Institute

Singapore, Singapore

RECRUITING

Central Study Contacts

Gemmy Cheung

CONTACT

+6563227460; gemmy.cheung.c.m@singhealth.com.sg

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: November 14, 2025
• First Posted: December 3, 2025
• Study Start: July 17, 2025
• Primary Completion (Estimated): July 1, 2028
• Study Completion (Estimated): July 1, 2028
• Last Updated: December 3, 2025

Record last verified: 2025-11

Locations

SG (1)