Laterality Success Determination of Microscopic Testicular Sperm Extraction in Non Obstructive Azoopsermia Patients

NCT07259967 | Not Yet Recruiting

• 1 other identifier: Laterality of micro TESE
• Study Type: observational
• Target: 80
• Locations: 0 countries
• Sites: N/A

Brief Summary

Determination of percentage of successful sperm retrieval in single testis in cases who will do bilateral TESE and identification factors mostly associated with successful sperm retrieval

Conditions

Testicular Sperm Extraction in Azoospermic Patients

Keywords

azoospermia; TESE

Outcome Measures

Primary Outcomes (1)

• percentage of successful sperm retrieval in single testis in cases who will do bilateral TESE.

  1 day Postoperative

Interventions

Testicular sperm extraction PROCEDURE

Bilateral Testicular sperm extraction done under microscopic guidance for non obstructive azoospermic patients

Eligibility Criteria

• Age: 20 Years - 60 Years
• Sex: male
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Male patients diagnosed as non obstructive azoospermia and will do bilateral TESE.

You may qualify if:

• Male patients diagnosed as non obstructive azoospermia.
• Will do bilateral TESE.

You may not qualify if:

• Obstructive azoospermia.
• Incomplete medical record .
• Prior testicular Trauma.

Sponsors & Collaborators

• Assiut University: lead

Related Publications (4)

• Raman JD, Schlegel PN. Testicular sperm extraction with intracytoplasmic sperm injection is successful for the treatment of nonobstructive azoospermia associated with cryptorchidism. J Urol. 2003 Oct;170(4 Pt 1):1287-90. doi: 10.1097/01.ju.0000080707.75753.ec.

  PMID: 14501743 RESULT

• Levin HS. Testicular biopsy in the study of male infertility: its current usefulness, histologic techniques, and prospects for the future. Hum Pathol. 1979 Sep;10(5):569-84. doi: 10.1016/s0046-8177(79)80100-8.

  PMID: 43278 RESULT

• Witt MA, Elsner C, Kort HI, Massey JB, Mitchell-Leef D, Toledo AA, Tucker MJ. A live birth from intracytoplasmic injection of a spermatozoon retrieved from testicular parenchyma. J Urol. 1995 Sep;154(3):1136-7. No abstract available.

  PMID: 7637066 RESULT

• Ichioka K, Matsui Y, Terada N, Negoro H, Goto T, Ogawa O. Three-dimensional simulation analysis of microdissection testicular sperm extraction for patients with non-obstructive azoospermia. Andrology. 2020 Sep;8(5):1214-1221. doi: 10.1111/andr.12812. Epub 2020 May 18.

  PMID: 32374923 RESULT

MeSH Terms

Conditions

Azoospermia

Condition Hierarchy (Ancestors)

Infertility, Male; Genital Diseases, Male; Genital Diseases; Urogenital Diseases; Infertility; Male Urogenital Diseases

Study Officials

• Mohamed Diab Mohamed Ramadan, Master

  Assiut University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Mohamed Diab, Master

CONTACT

01005886962; md01147169166@gmail.com

Mohamed D Mohamed, Master

CONTACT

01501501772; md01501501772@gmail.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Lecturer

Study Record Dates

• First Submitted: November 20, 2025
• First Posted: December 2, 2025
• Study Start: December 1, 2025
• Primary Completion (Estimated): December 1, 2026
• Study Completion (Estimated): January 1, 2027
• Last Updated: December 2, 2025

Record last verified: 2025-11