PET-CT in Lymphoma Among the Eldery

NCT07259941 | Not Yet Recruiting

• 1 other identifier: PET-CT Imaging in Lymphoma
• Study Type: observational
• Target: 63
• Locations: 0 countries
• Sites: N/A

Brief Summary

This study investigates PET-CT imaging patterns and metabolic parameters in elderly patients (≥60 years) diagnosed with lymphoma, aiming to enhance diagnostic accuracy and prognosis using 18F-FDG PET/CT scans.

Conditions

PET-CT; Lymphoma; Elderly; Metabolic Parameters

Keywords

PET-CT; Lymphoma; Elderly; metabolic parameters

Outcome Measures

Primary Outcomes (1)

• FDG-PET/CT Imaging Pattern Description in Elderly Lymphoma Patients

  The main outcome is the characterization of metabolic and anatomical findings from 18F-FDG PET/CT scans among elderly patients (≥60 years) diagnosed with lymphoma. This includes describing the visual appearance, extent, and distribution of disease lesions observed on initial imaging.

  At time of initial PET/CT scan performed as part of routine clinical evaluation

Eligibility Criteria

• Age: 60 Years+
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The participants include elderly patients (≥60 years) with confirmed lymphoma diagnosis through histopathological examination. Excluded are individuals with other active cancers or uncontrolled diabetes mellitus (blood glucose \> 200 mg/dL), which could interfere with PET scan accuracy. Patients must have fasting blood glucose \< 200 mg/dL before 18F-FDG injection and are prepared per standardized protocols. The sample size is calculated to be approximately 63 patients, providing adequate statistical power based on confidence limits and previous positive PET findings in elderly lymphoma cohorts.

You may qualify if:

• \- Age ≥ 60 years
• Histopathological diagnosis of lymphoma

You may not qualify if:

• \- Presence of other concurrent active malignancies
• Uncontrolled diabetes mellitus with blood glucose \> 200 mg/dL at the time of PET/CT scan

Sponsors & Collaborators

• Assiut University: lead

MeSH Terms

Conditions

Lymphoma

Condition Hierarchy (Ancestors)

Neoplasms by Histologic Type; Neoplasms; Lymphoproliferative Disorders; Lymphatic Diseases; Hemic and Lymphatic Diseases; Immunoproliferative Disorders; Immune System Diseases

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Resident at Nuclear Medicine unit, Radiotherapy and Nuclear Medicine Department, South Egypt Cancer Institute

Study Record Dates

• First Submitted: November 21, 2025
• First Posted: December 2, 2025
• Study Start: January 1, 2026
• Primary Completion (Estimated): January 1, 2027
• Study Completion (Estimated): February 1, 2027
• Last Updated: December 2, 2025

Record last verified: 2025-11