Effect of Stretching Exercises Versus Aerobic Exercises on Preeclampsia

NCT07255677 | Not Yet Recruiting

• 1 other identifier: P.T.REC/012/005974
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of the study is to compare between the effect of stretching exercises and aerobic exercises on preeclampsia.

Conditions

Preeclampsia

Outcome Measures

Primary Outcomes (2)

• Measurement of arterial blood pressure

  Arterial blood pressure will be measured from the right arm while the woman is in a half-lying position. The measurement will be the mean of three trials. Each woman in both groups will be assessed before and after the six-week treatment period.

  6 weeks

• Measurement of proteinuria

  Each woman in both groups will be asked to collect a 24-hour urine sample in sterilized glass bottles for measurement of protein levels. This collection will take place before and after the six-week treatment period.

  6 weeks

Secondary Outcomes (1)

• Body mass index (BMI) measurement

  6 weeks

Study Arms (2)

Stretching exercises program + Antihypertensive drugs

EXPERIMENTAL

It will consist of 30 women with mild preeclampsia. They will be treated with a stretching exercise program, conducted three times per week for six weeks, alongside antihypertensive drugs.

Other: Stretching exercises program; Drug: Antihypertensive drugs

Aerobic exercises program + Antihypertensive drugs

EXPERIMENTAL

It will consist of 30 women with mild preeclampsia. They will be treated with an aerobic exercise program, conducted three times per week for six weeks, alongside antihypertensive drugs.

Other: Aerobic exercises program; Drug: Antihypertensive drugs

Interventions

Stretching exercises program OTHER

Each woman in the first experimental group will follow a supervised stretching exercise program three times per week for six weeks. Sessions will begin with deep breathing warm-up, followed by stretching each target muscle for 10 seconds with 10 seconds relaxation for the first two weeks, 15 seconds stretching and relaxation in weeks three and four, and 20 seconds in weeks five and six. Each stretch will be repeated 10 times per session. After six weeks, women will be instructed to continue these exercises until delivery.

Stretching exercises program + Antihypertensive drugs

Aerobic exercises program OTHER

The second experimental group will follow a supervised aerobic exercise program of mild to moderate intensity (40%-60% HRmax, calculated as 220 minus age). Heart rate will be monitored before and during exercise. The program, conducted three times per week for six weeks, will start with a 5-minute low-speed walking warm-up. In the first two weeks, this will be followed by 10 minutes on a treadmill (King Fitness Model 8000AC), 5 minutes relaxation, 10 minutes on a stationary bike (GRASP93026), and 5 minutes relaxation. In weeks three and four, treadmill and bike sessions will increase to 15 minutes each, with 10 minutes relaxation between. In weeks five and six, treadmill and bike time will increase to 20 minutes, with 15 minutes relaxation between. After six weeks, women will continue these exercises until delivery.

Aerobic exercises program + Antihypertensive drugs

Antihypertensive drugs DRUG

All women in both groups will be treated by antihypertensive drugs (labipress) for 6 weeks.

Also known as: labipress

Aerobic exercises program + Antihypertensive drugs; Stretching exercises program + Antihypertensive drugs

Eligibility Criteria

• Age: 20 Years - 30 Years
• Sex: female
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Their ages ranged from 20-30 years old.
• Their body mass index (BMI) didn't exceed 35 Kg\\m2.
• All women primigravida.
• All women are complaining of mild preeclampsia.

You may not qualify if:

• Chronic disease (diabetes mellitus, thyroid, hypertension, nephrotic).
• Vaginal bleeding.
• Placenta previa.
• Physical and psychological disorders.

Sponsors & Collaborators

• Cairo University: lead

Study Sites (1)

Cairo University

Giza, Egypt

Location

MeSH Terms

Conditions

Pre-Eclampsia

Interventions

Antihypertensive Agents

Condition Hierarchy (Ancestors)

Hypertension, Pregnancy-Induced; Pregnancy Complications; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases

Intervention Hierarchy (Ancestors)

Cardiovascular Agents; Therapeutic Uses; Pharmacologic Actions; Chemical Actions and Uses

Study Officials

• Mohamed Ahmad Mohamed Awad, PhD

  Professor, Cairo university

  STUDY CHAIR

• Mai Mohamed Ali, PhD

  Assistant Professor, Cairo University

  STUDY DIRECTOR

• Amir Araby Gabre, PhD

  Professor, Cairo university

  STUDY DIRECTOR

Central Study Contacts

Mai Khaled Abdrabo Naeem, B.Sc

CONTACT

+20 102 176 6648; maikhaled2594@yahoo.com

Mai Mohamed Ali, PhD

CONTACT

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: November 20, 2025
• First Posted: December 1, 2025
• Study Start: November 30, 2025
• Primary Completion: January 15, 2026
• Study Completion: January 20, 2026
• Last Updated: December 1, 2025

Record last verified: 2025-11

Locations

EG (1)