NCT07250113

Brief Summary

The goal of this clinical trial is to learn if a newly-created website tool, called WeCareToFeedDysphagia, helps to reduce feelings of burden in care partners of patients with Alzheimer's disease and related dementias (AD/ADRD) who were diagnosed with trouble swallowing (oropharyngeal dysphagia). The main questions this study aims to answer are:

  • How effective is the WeCareToFeedDysphagia tool in reducing feelings of burden in care partners?
  • Does the WeCareToFeed Dysphagia tool help improve patient outcomes?
  • Does care partner age, gender, and patient dysphagia severity impact the strength of the effect of the WeCareToFeedDysphagia tool?
  • Is the strength of the effect of the WeCareToFeedDysphagia tool impacted by care partner's beliefs in being able to manage behavior and stress (self-efficacy)? Researchers will compare a group of care partners who have access to the WeCareToFeedDysphagia tool (intervention) to a group of care partners who do not have access to the tool. Both groups will receive contact information for help from a speech language pathologist expert (enhanced usual care). Participants will:
  • be given access to the web tool and receive 3 text message reminders over 3 weeks to use the tool (intervention group only).
  • be asked to complete a remote, web-based survey three times: when enrolled in the study, at 1 month following patient leaving the hospital, and at 3 months following patient leaving the hospital.

Trial Health

75
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
802

participants targeted

Target at P75+ for not_applicable

Timeline
21mo left

Started Feb 2026

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
enrolling by invitation

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress9%
Feb 2026Jan 2028

First Submitted

Initial submission to the registry

November 18, 2025

Completed
8 days until next milestone

First Posted

Study publicly available on registry

November 26, 2025

Completed
3 months until next milestone

Study Start

First participant enrolled

February 17, 2026

Completed
1.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2028

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2028

Last Updated

March 16, 2026

Status Verified

March 1, 2026

Enrollment Period

1.9 years

First QC Date

November 18, 2025

Last Update Submit

March 13, 2026

Conditions

Outcome Measures

Primary Outcomes (1)

  • Mean Care Partner Burden at 3 Months Post Hospital Discharge

    Burden will be measured using the Zarit Burden Scale (ZBI-22), a validated measure that assesses 22 statements related to personal strain accompanying caring for another person, which is rated with 5 frequency-related response categories, scored 0 (never) to 4 (nearly always). The total score ranges between 0 and 88 (higher scores indicating higher burden). A score greater than 21 has been suggested to indicate care-partner burden. Outcome measures will be captured through a link to an online questionnaire which will be sent to the care partner's smart phone/device via text message.

    3 months from hospital discharge

Secondary Outcomes (4)

  • Mean Care Partner Burden at 1 Month Post Hospital Discharge

    1 month from hospital discharge

  • Mean Care Partner Quality of Life at 1 Month Post Hospital Discharge

    1 month from hospital discharge

  • Mean Care Partner Quality of Life at 3 Months Post Hospital Discharge

    3 months from hospital discharge

  • Percent Engagement with the WeCareToFeedDysphagia Tool

    3 months from hospital discharge

Other Outcomes (16)

  • Mean CARES Part A at 1 Month Post Hospital Discharge

    1 month from hospital discharge

  • Mean CARES Part A at 3 Months Post Hospital Discharge

    3 months from hospital discharge

  • Mean CARES Part B at 1 Month Post Discharge

    1 month from hospital discharge

  • +13 more other outcomes

Study Arms (2)

Enhanced Control + WeCareToFeedDysphagia

EXPERIMENTAL

Participants receive usual care from their medical team and receive contact information for speech-language pathology follow-up care. Participants will also receive access to the WeCareToFeedDysphagia web tool and receive text message reminders to use the tool.

Behavioral: WeCareToFeedDysphagia web tool

Enhanced Control

NO INTERVENTION

Participants receive usual care from their medical team and receive contact information for speech-language pathology follow-up care.

Interventions

The web tool uses written and video content, care-partner testimonials, frequently asked questions, and resource links to provide accurate information (e.g., dysphagia diets), set realistic expectations, identify/support feeding goals (quality of life considerations), acknowledge/support care-partner feelings, and provide competencies/skills for oropharyngeal dysphagia (OD) management.

Enhanced Control + WeCareToFeedDysphagia

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Self-identifies as the primary care partner of an older adult patient (patient age ≥ 65 years) with AD/ADRD and oropharyngeal dysphagia (OD) admitted to the Northwell medicine service
  • Age ≥ 18 years
  • Designated as the legally authorized representative (LAR) or health care proxy (HCP), or designated by the LAR or HCP to participate
  • Proficient in English
  • Has access to a device (e.g. smartphone, iPad, computer) capable of accessing a web browser

You may not qualify if:

  • Care partner of patient with a percutaneous feeding tube (i.e. PEG, PEJ used exclusively)
  • Care partner of patient who will not be discharged to the home or community setting (e.g., home, assisted living, independent living)
  • Care partner will not be involved with OD management (e.g. buying or making food, feeding, supervising) after hospital discharge

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

The Feinstein Institutes for Medical Research

Manhasset, New York, 11030, United States

Location

MeSH Terms

Conditions

Caregiver BurdenAlzheimer DiseaseDementiaDeglutition Disorders

Condition Hierarchy (Ancestors)

Stress, PsychologicalBehavioral SymptomsBehaviorBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesTauopathiesNeurodegenerative DiseasesNeurocognitive DisordersMental DisordersEsophageal DiseasesGastrointestinal DiseasesDigestive System DiseasesPharyngeal DiseasesOtorhinolaryngologic Diseases

Study Officials

  • Liron Sinvani, MD

    Northwell Health

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor

Study Record Dates

First Submitted

November 18, 2025

First Posted

November 26, 2025

Study Start

February 17, 2026

Primary Completion (Estimated)

January 1, 2028

Study Completion (Estimated)

January 1, 2028

Last Updated

March 16, 2026

Record last verified: 2026-03

Data Sharing

IPD Sharing
Will share

All data which can be sufficiently deidentified to preserve participant confidentiality will be made available via the Open Science Framework (OSF) repository. The goal of all shared data will be to facilitate replication of all primary and secondary, and exploratory study analyses as well as to allow for additional analyses with available data. Data will be redacted according to the safe-harbor method, and effective strategies will be adopted to minimize risk of disclosing a participant's identity. Data will be shared along with documentation of how variables were cleaned, coded, or summarized. In cases where participant-level data could be used to identify individuals, summary data will be presented (e.g. presenting an age category "\>85 years old" rather than individual participant age). Information about how summary data was generated will be provided in the data dictionary.

Shared Documents
STUDY PROTOCOL, SAP, ICF
Time Frame
Study data and metadata will be available in advance of the first online publication of the primary study outcomes. De-identified data will be stored on OSF indefinitely to allow for continued access.
Access Criteria
Deidentified data will be made publicly available.

Locations