NCT07249970

Brief Summary

The study is an open prospective cohort study. Participants are assessed at the start of their care in an addiction treatment unit using the Addiction Severity Index (ASI) and the Mini International Neuropsychiatric Interview (MINI), which are routinely conducted in these centers for individuals with substance use or behavioral disorders. After the study protocol is explained, the evaluator checks eligibility criteria, interested participants provide their written informed consent. The evaluator invites participants to complete self-administered questionnaires at home, which are returned during a session that also includes cognitive testing. Follow-up interviews are scheduled at 3 months, 6 months, and every 6 months thereafter.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
10,000

participants targeted

Target at P75+ for all trials

Timeline
118mo left

Started Mar 2002

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress71%
Mar 2002Dec 2035

Study Start

First participant enrolled

March 12, 2002

Completed
23.6 years until next milestone

First Submitted

Initial submission to the registry

September 29, 2025

Completed
2 months until next milestone

First Posted

Study publicly available on registry

November 25, 2025

Completed
5.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2030

Expected
5 years until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2035

Last Updated

November 25, 2025

Status Verified

November 1, 2025

Enrollment Period

28.8 years

First QC Date

September 29, 2025

Last Update Submit

November 24, 2025

Conditions

Keywords

Addictionaddictive behavioraddiction disorders

Outcome Measures

Primary Outcomes (1)

  • Severity of addiction

    ASI composite score

    at Day 0, at Month 3, at Month 6 and at each following 6-month visit

Study Arms (1)

Usual care

Other: Addiction Severity Index

Interventions

Once recruited, self-questionnaires completed by the participant at home and brought back at next visite, during which the participant takes cognitive tests. Follow-up interviews are scheduled at 3 months, 6 months, and then every 6 months.

Usual care

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Healthcare units : CSAPA de Bordeaux and CSAPA de Bayonne.

You may qualify if:

  • Presenting with at least one substance or behavioral addiction (according to DSM5 criteria)

You may not qualify if:

  • Condition incompatible with understanding assessment tools
  • Difficulties understanding and/or writing French
  • Person unable to give personal consent

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Centre Hospitalier CHARLES PERRENS

Bordeaux, Gironde, 33076, France

RECRUITING

Related Publications (3)

  • Petry NM, Blanco C, Auriacombe M, Borges G, Bucholz K, Crowley TJ, Grant BF, Hasin DS, O'Brien C. An overview of and rationale for changes proposed for pathological gambling in DSM-5. J Gambl Stud. 2014 Jun;30(2):493-502. doi: 10.1007/s10899-013-9370-0.

  • Hasin DS, O'Brien CP, Auriacombe M, Borges G, Bucholz K, Budney A, Compton WM, Crowley T, Ling W, Petry NM, Schuckit M, Grant BF. DSM-5 criteria for substance use disorders: recommendations and rationale. Am J Psychiatry. 2013 Aug;170(8):834-51. doi: 10.1176/appi.ajp.2013.12060782.

  • O'Brien C. Addiction and dependence in DSM-V. Addiction. 2011 May;106(5):866-7. doi: 10.1111/j.1360-0443.2010.03144.x. Epub 2010 Oct 6.

MeSH Terms

Conditions

Behavior, Addictive

Condition Hierarchy (Ancestors)

Compulsive BehaviorImpulsive BehaviorBehavior

Study Officials

  • Marc AURIACOMBE, Prof Md PhD

    CH. Charles Perrens

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Marc AURIACOMBE, Prof, MD, PhD

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Target Duration
5 Years
Sponsor Type
OTHER GOV
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 29, 2025

First Posted

November 25, 2025

Study Start

March 12, 2002

Primary Completion (Estimated)

December 31, 2030

Study Completion (Estimated)

December 31, 2035

Last Updated

November 25, 2025

Record last verified: 2025-11

Locations