Prognosis of Behavioral Addiction in Parkinson's Disease

NCT02671240 | Terminated

• 1 other identifier: 6246
• Study Type: observational
• Target: 164
• Locations: 1 country
• Sites: 1

Brief Summary

Our hypothesis is that the conventional treatment of Behavioral Addiction in Parkinson's disease is often not effective, and that affects the motor aspects (worsening akinéto-rigid syndrome and / or worsening of dyskinesia due to higher levodopa doses to compensate for the drop in behavioral addictions) and non-motor (withdrawal syndrome dopamine agonist) anxiously including apathy. Our goal is to describe the natural history of Behavioral Addiction under the effect of the evolution of the disease and adapt treatment according to the prior art, through a study of a larger population of patients than in the few published studies.

Conditions

Addiction

Keywords

Parkinson disease; behavioral addiction; akinéto-rigid syndrome; dopamine agonist

Outcome Measures

Primary Outcomes (1)

• Survival time before disappearance of behavioral addiction defined by a score of less than 2 on the scale of behavioral assessment of Parkinson's disease

  12 months after selection

Study Arms (2)

- Patients with behavioral addiction

- Patients with no behavioral addiction

Eligibility Criteria

• Age: 30 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients with Parkinson's disease who developed or not a behavioral addiction

You may qualify if:

• Age greater than or equal to 30 years
• Parkinson's disease according to the criteria of UKPDSBB
• Time evolution of the top disease or equal to 5 years

You may not qualify if:

• Lack of Parkinson's disease and atypical parkinsonism
• Patient not previously included in PD-BADGE

Sponsors & Collaborators

• University Hospital, Strasbourg, France: lead

Study Sites (1)

Service de Neurologie

Strasbourg, 67098, France

Location

MeSH Terms

Conditions

Behavior, Addictive; Parkinson Disease

Condition Hierarchy (Ancestors)

Compulsive Behavior; Impulsive Behavior; Behavior; Parkinsonian Disorders; Basal Ganglia Diseases; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Movement Disorders; Synucleinopathies; Neurodegenerative Diseases

Study Officials

• Mathieu ANHEIM, MD, PhD

  University Hospital, Strasbourg, France

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: January 18, 2016
• First Posted: February 2, 2016
• Study Start: October 24, 2016
• Primary Completion: April 19, 2019
• Study Completion: April 19, 2019
• Last Updated: August 23, 2023

Record last verified: 2023-08

Data Sharing

• IPD Sharing: Will not share

Locations

FR (1)