Establishment of Hong Kong Diabesity Register

NCT07247409 | Recruiting

• 1 other identifier: CRE 2025.324 register
• Study Type: observational
• Target: 800
• Locations: 1 country
• Sites: 1

Brief Summary

All participants of the Diabesity Register will receive structured assessment by nurses guided by the JADE portal at baseline including eye, feet, blood and urine examination with evaluation of BMI, blood pressure, HbA1c, lipid profile, renal and liver function tests, urine for albumin-creatinine ratio. All patients will return at 3-year for a repeat assessment of physical and psychological health, as well as changes over time.

Conditions

Diabesity

Outcome Measures

Primary Outcomes (1)

• A composite of incidence

  Incidence of diabetes-related complications

  3 years

Secondary Outcomes (6)

• Incidence of diabetic mellitus retinopathy

  3 years

• Incidence of diabetic mellitus nephropathy

  3 years

• Incidence of diabetic mellitus neuropathy

  3 years

• Incidence of myocardial infarction

  3 years

• Incidence of stroke

  3 years

Study Arms (1)

Diabesity

People with diabetes and obesity

Other: No Intervention: Observational Cohort

Interventions

No Intervention: Observational Cohort OTHER

It is an registry so no intervention will be used.

Diabesity

Eligibility Criteria

• Age: 18 Years - 50 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

All study subjects will be recruited from the Diabetes Mellitus and Endocrine Centre (DMEC) at PWH. Since 1995, the PWH runs a comprehensive complication screening program as part of a quality improvement program in the DMEC. On a weekly basis, patients with diabetes mellitus undergo comprehensive assessments for risk factors and complications by nurses and health care assistants using standard protocols.

You may qualify if:

• Type 2 diabetes;
• Obesity reaching action level as defined as body mass index (BMI) 27.5 kg/m2 and/or waist circumference (WC) 80cm in women and 90cm in men;
• Age between 18 and 50 years;
• Able to conversate with smartphone technology and web-based program.
• Able to read Chinese and communicate using Chinese.

You may not qualify if:

• Type 1 diabetes;
• Active malignant disease including those with history of malignant disease less than 5 years of disease-free duration;
• Life expectancy less than 12 months;
• Any medical illness or condition as judged by the investigators as ineligible to participate the study.

Sponsors & Collaborators

• Chinese University of Hong Kong: lead

Study Sites (1)

Department of Medicine and Therapeutics, The Chinese University of Hong Kong (CUHK), Ward 3M, Diabetes and Endocrine Research Centre, 3/F Day Treatment Block and Children Wards (Old Block), Prince of Wales Hospital

Hong Kong, Hong Kong

RECRUITING

MeSH Terms

Conditions

Diabesity

Condition Hierarchy (Ancestors)

Diabetes Complications; Diabetes Mellitus; Endocrine System Diseases; Obesity; Overweight; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Central Study Contacts

Alice Pik Shan Kong, MD

CONTACT

+852 3505 2648; alicekong@cuhk.edu.hk

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 3 Years
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: November 18, 2025
• First Posted: November 25, 2025
• Study Start: October 22, 2025
• Primary Completion (Estimated): December 31, 2026
• Study Completion (Estimated): December 31, 2029
• Last Updated: November 25, 2025

Record last verified: 2025-10

Locations

HK (1)