A Chaplain-clinician Led Spiritual Care (PEACE) Intervention on Spiritual/Religious Beliefs Related to Medical Care in Patients With Advanced Cancer: a Pilot Clinical Trial

NCT07246954 | Recruiting DMC

• 2 other identifiers: 2025-1052NCI-2025-08254
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

To examine the feasibility and acceptability of chaplain-clinician led spiritual care (PEACE: Perception, Exploring, Addressing, Compassionate Connection, Embracing) intervention in patients with advanced cancer.

Conditions

Spiritual Care; Advanced Cancer

Outcome Measures

Primary Outcomes (1)

• RBEC Questionnaire

  Through study completion; an average of 1 year

Study Arms (2)

Phase 1

EXPERIMENTAL

Patients will participate in two PEACE intervention sessions, which will last 30-60 minutes each.

Other: Peace Intervention

Phase 2

EXPERIMENTAL

Usual care is a comprehensive evaluation of the physical, emotional, and spiritual needs of the patient by the Supportive/Palliative Care medical team

Other: Peace Intervention; Other: Usual Care

Interventions

Peace Intervention OTHER

Patients will participate in two PEACE intervention sessions, which will last 30-60 minutes each.

Phase 1; Phase 2

Usual Care OTHER

Usual care is a comprehensive evaluation of the physical, emotional, and spiritual needs of the patient by the Supportive/Palliative Care medical team.

Phase 2

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

Eligibility Criteria 1. Participants with advanced cancer (locally advanced, metastatic, recurrent, or incurable) seen by the participant supportive/palliative care mobile team at MD Anderson Cancer Center. 2. Respond "somewhat to A great deal" to the question in the RBEC questionnaire "I will accept every possible medical treatment because my faith tells me to do everything I can to stay alive longer". 3. Participant s aged 18 years or over. 4. Karnofsky performance status ≥30% at time of inclusion into study. 5. Normal cognitive status as determined by the supportive care clinicians based on the ability to understand the nature of the study and consent process. 6. Only English-speaking, as determined by their ability to understand the informed consent, the intervention, and the assessment tools.

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

• M.D. Anderson Cancer Center: lead

Study Sites (1)

MD Anderson Cancer Center

Houston, Texas, 77030, United States

RECRUITING

Related Links

• MD Anderson Cancer Center

Study Officials

• Marvin Delgado Guay, MD

  M.D. Anderson Cancer Center

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Marvin Delgado Guay, MD

CONTACT

713-745-8190; marvin.delgado@mdanderson.org

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: SUPPORTIVE CARE
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 4, 2025
• First Posted: November 24, 2025
• Study Start: December 22, 2025
• Primary Completion (Estimated): January 1, 2027
• Study Completion (Estimated): January 1, 2029
• Last Updated: February 6, 2026

Record last verified: 2026-02

Locations

US (1)