Epidural Catheter and Port-Related Infections in Pain Clinic Patients

NCT07242560 | Active Not Recruiting

• 1 other identifier: Mersin-ALG-ECPI-2025
• Study Type: observational
• Target: 351
• Locations: 1 country
• Sites: 1

Brief Summary

This retrospective observational study aims to evaluate the incidence and risk factors of infection associated with epidural catheter and port applications performed in the Pain Clinic of Mersin University Faculty of Medicine. Data from patients who underwent epidural catheter or port placement between January 2002 and January 2025 will be analyzed. Demographic data, catheter duration, insertion level, type of device, clinical indication, and microbiological culture results will be examined to determine factors influencing infection development. The study seeks to identify common pathogens and assess potential relationships between procedural characteristics and infection risk. The ultimate goal of this research is to contribute to improving infection prevention strategies and ensuring patient safety in interventional pain management practices.

Conditions

Epidural Catheter-Related Infection; Hospital-Acquired Infection; Procedural Complication

Keywords

Epidural catheter; Epidural port; Infection; Pain clinic; Interventional pain management

Outcome Measures

Primary Outcomes (1)

• Incidence of Infection Associated With Epidural Catheter or Port Use

  The proportion of patients who developed infection following epidural catheter or port placement, confirmed either clinically or microbiologically (positive culture from catheter tip or port site).

  From date of catheter or port placement until device removal or completion of follow-up (within study period January 2002-January 2025).

Secondary Outcomes (1)

• Risk Factors Associated With Infection Development

  Throughout the duration of catheter or port use, within the study period (January 2002-January 2025).

Study Arms (2)

Epidural Catheter Group

Patients who underwent epidural catheter insertion for pain management between January 2002 and December 2022 at the Mersin University Pain Clinic. Data include catheter duration, insertion site, indication, and culture results.

Epidural Port Group

Patients who received epidural port placement for long-term analgesic management during the same period. Data include port type, indication, duration of use, and infection outcomes.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients treated at the Pain Clinic of Mersin University Faculty of Medicine who received epidural catheter or port applications for pain management between 2002 and 2025.

You may qualify if:

• Patients aged 18 years and older.
• Patients who underwent epidural catheter or epidural port application at Mersin University Pain Clinic between January 1, 2002 and January 1, 2025.
• Complete clinical records including demographic data, procedural details, and culture results available for review.

You may not qualify if:

• Patients with incomplete or missing procedural or infection data.
• Patients whose records do not include culture or infection status documentation.
• Patients younger than 18 years old.

Sponsors & Collaborators

• Mesut Bakır: lead

Study Sites (1)

Mersin University Faculty of Medicine, Department of Algology

Mersin, Mersin, 33110, Turkey (Türkiye)

Location

Related Publications (2)

• Horlocker TT, Wedel DJ. Infectious complications of regional anesthesia. Best Pract Res Clin Anaesthesiol. 2008 Sep;22(3):451-75. doi: 10.1016/j.bpa.2008.06.003.

  PMID: 18831298 BACKGROUND

• Domingues C, Goncalves L, Laranjo M, Santos T, Goncalves D, Goncalves L, Barros AC, Marrao G, Castro R, Valente E. Epidural Catheter Bacterial Colonization and Infection in a Secondary Portuguese Hospital Setting. Cureus. 2024 Oct 26;16(10):e72428. doi: 10.7759/cureus.72428. eCollection 2024 Oct.

  PMID: 39588402 BACKGROUND

MeSH Terms

Conditions

Cross Infection; Infections

Condition Hierarchy (Ancestors)

Iatrogenic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Mesut Bakır, Assoc. Prof

  Mersin University Faculty of Medicine, Pain Clinic

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Assoc. Prof. Dr. Mesut Bakır, Mersin University Faculty of Medicine, Department of Algology

Study Record Dates

• First Submitted: November 17, 2025
• First Posted: November 21, 2025
• Study Start: January 1, 2002
• Primary Completion: January 1, 2025
• Study Completion: December 1, 2025
• Last Updated: November 21, 2025

Record last verified: 2025-10

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)