Comparative Study of Novel Prognostic Scores in Patients With Liver Cirrhosis
1 other identifier
observational
100
0 countries
N/A
Brief Summary
- 1.To determine the prognostic performance of novel scores in predicting complications and in-hospital mortality in patients with liver cirrhosis.
- 2.To compare the accuracy of these scores in identifying high risk patients relative to the standard scores.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Dec 2025
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
November 16, 2025
CompletedFirst Posted
Study publicly available on registry
November 20, 2025
CompletedStudy Start
First participant enrolled
December 1, 2025
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2026
ExpectedStudy Completion
Last participant's last visit for all outcomes
January 1, 2027
November 20, 2025
November 1, 2025
1 year
November 16, 2025
November 16, 2025
Conditions
Outcome Measures
Primary Outcomes (1)
Comparative study of novel prognostic scores for prediction of morbidity and mortality in patients with liver cirrhosis
Usage of new prognostic scores for prediction of morbidity and mortality in patients with LC
baseline
Interventions
usage of new scores for prediction of morbidity and mortality in patients with liver cirrhosis
Eligibility Criteria
This study based on patients with Liver Cirrhosis
You may qualify if:
- Age ≥ 18 years
- Diagnosis of liver cirrhosis (clinical, radiological using ultrasound or fibroscan)
- Hospital admission for acute decompensation (ascites, hepatic encephalopathy, variceal bleeding, SBP)
- Pregnancy
- Refusal to participate in the study riteria:
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Related Publications (2)
Jalan R, Saliba F, Pavesi M, Amoros A, Moreau R, Gines P, Levesque E, Durand F, Angeli P, Caraceni P, Hopf C, Alessandria C, Rodriguez E, Solis-Munoz P, Laleman W, Trebicka J, Zeuzem S, Gustot T, Mookerjee R, Elkrief L, Soriano G, Cordoba J, Morando F, Gerbes A, Agarwal B, Samuel D, Bernardi M, Arroyo V; CANONIC study investigators of the EASL-CLIF Consortium. Development and validation of a prognostic score to predict mortality in patients with acute-on-chronic liver failure. J Hepatol. 2014 Nov;61(5):1038-47. doi: 10.1016/j.jhep.2014.06.012. Epub 2014 Jun 17.
PMID: 24950482RESULTAsrani SK, Devarbhavi H, Eaton J, Kamath PS. Burden of liver diseases in the world. J Hepatol. 2019 Jan;70(1):151-171. doi: 10.1016/j.jhep.2018.09.014. Epub 2018 Sep 26.
PMID: 30266282RESULT
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- CASE CROSSOVER
- Time Perspective
- CROSS SECTIONAL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Dr
Study Record Dates
First Submitted
November 16, 2025
First Posted
November 20, 2025
Study Start
December 1, 2025
Primary Completion (Estimated)
December 1, 2026
Study Completion (Estimated)
January 1, 2027
Last Updated
November 20, 2025
Record last verified: 2025-11
Data Sharing
- IPD Sharing
- Will not share