Adenomyosis Clinical, Imaging and Histopathology

NCT07237932 | Enrolling By Invitation DMC

• 1 other identifier: KFSIRH200-573
• Study Type: observational
• Target: 32
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this clinical trial is to identify and compare the results of imaging studies and evaluating adenomyosis features and post hysterectomy results and their clinical relievants as well as to describe classification for adenomyosis based on one or a combination of clinical, imaging and histopathological features. Main questions it aim to answer: What's the relation between clinical symptoms ,maging and histopathological classification of adenomyosis? Research will identify relationships between clinical symptoms, imaging and histopathological classification of adenomyosis Participants will undergo transvaginal ultrasound, non contrast pelvic MRI, hysterectomy then histopathological examination for their uterus

Conditions

Adenomyosis

Outcome Measures

Primary Outcomes (1)

• Classifications of adenomyosis

  Class of adenomyosis according to imaging, histopathology and clinical outcomes

  12 months

Eligibility Criteria

• Age: 35 Years - 55 Years
• Sex: female
• Healthy Volunteers: No
• Age Groups: Adult (18-64)
• Sampling Method: Probability Sample

Study Population

Female patient multipara complete their family who has heavy menstrual bleeding due to adenomyosis with failure of medical treatment

You may qualify if:

• Age from 35 to 55 years old female No previous hormonal treatment for uterine adenomyosis within three months Women with heavy menstrual bleeding and dysmenorrhoea Women who completed their families Patient failed medical treatment and hysterectomy is the only remaining line for treatment -

You may not qualify if:

• Patients not candidate for hysterectomy Positive pregnancy test Patients with contraindications for MRI such as patients with pacemakers, claustrophobia,or other implanted electronic devices Inadequate image quality due to motion artifact

Sponsors & Collaborators

• Kafrelsheikh University: lead

Study Sites (1)

Kafr elsheikh university

Kafr ash Shaykh, Egypt

Location

MeSH Terms

Conditions

Adenomyosis

Condition Hierarchy (Ancestors)

Uterine Diseases; Genital Diseases, Female; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Genital Diseases

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: PROSPECTIVE
• Target Duration: 2 Weeks
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Resident

Study Record Dates

• First Submitted: November 15, 2025
• First Posted: November 20, 2025
• Study Start: April 30, 2025
• Primary Completion: April 30, 2026
• Study Completion: June 30, 2026
• Last Updated: July 8, 2026

Record last verified: 2026-07

Locations

EG (1)