The Effect of Quadriceps Sets Exercise on Knee Joint Biomechanics and Functional Outcomes of Post-Total Knee Arthroplasty Patients

NCT07233005 | Completed DMC

• 1 other identifier: 10-03-46
• Study Type: interventional
• Target: 36
• Locations: 1 country
• Sites: 1

Brief Summary

Lower limb strengthening, especially the quadriceps training, is of much necessity for patients with knee arthroplasty. As the quadriceps strengthening exercises play a vital role in controlling gait pattern during walking and different activities. Vastus inetrmedius muscle responsible for the last 10 degree of knee extension. This enable the knee joint to be in locked position which is the stable position during gait.

Conditions

Total Knee Arthroplasty

Outcome Measures

Primary Outcomes (2)

• Visual Analoge Scale (VAS)

  VAS is a straight horizontal line of usually 100 mm. The ends are defined as the extreme limits of the pain . It is orientated from the left (worst) to the right (least) pain.

  Four weeks

• Quadriceps Muscle Strength

  it will be measured using a hand held dynamometer.

  4 weeks

Secondary Outcomes (3)

• Range of Motion (ROM)

  4 weeks

• Oxford Knee Score (OKS)

  4 weeks

• The Western Ontario and McMaster Universities Osteoarthritis Index (The WOMAC)

  4 weeks

Study Arms (2)

Quadriceps Set & Terminal Knee Extension Exercises Group (Study Group)

EXPERIMENTAL

Procedure: Quadriceps Set Exercise; Procedure: Terminal Knee Extension; Procedure: Traditional Physical Therapy

Traditional Physical Therapy Group (Control Group)

EXPERIMENTAL

Procedure: Traditional Physical Therapy

Interventions

Quadriceps Set Exercise PROCEDURE

Quadriceps knee set exercises was introduced with the patient in sitting position and pillow was placed under his knee joint then ask patient to dorsiflex his ankle and extend knee make hold 10 second then relax. Two exercises session per week for four week.

Quadriceps Set & Terminal Knee Extension Exercises Group (Study Group)

Terminal Knee Extension PROCEDURE

Terminal knee extension exercise using Thera band was introduced with the patient in sitting or standing position and the theraband was placed around his knee joint. Two exercises session per week for four week.

Quadriceps Set & Terminal Knee Extension Exercises Group (Study Group)

Traditional Physical Therapy PROCEDURE

Traditional physical therapy program will include passive stretching exercise to the hamstrings while the patient is supine lying flex the hip while the knee extended and hold for 30-45 seconds, strengthening exercise to the guadriceps muscle by extending the knee whie the patient is in the sitting position.

Quadriceps Set & Terminal Knee Extension Exercises Group (Study Group); Traditional Physical Therapy Group (Control Group)

Eligibility Criteria

• Age: 40 Years - 60 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Age (ranging from 40 to 60 years old).
• Weight (ranging from 65 to 75 kg).
• Height (ranging from 150 to 165 cm)
• Sex ( male/ female).
• Patients who undergoing total knee arthroplasty after 1 months until one year after operation.

You may not qualify if:

• Cognitive impairment.
• Neuromuscular impairment.
• Patient can't walk alone (need of assistive device).

Sponsors & Collaborators

• Cairo University: lead

Study Sites (1)

Jouf University

Sakakah, Saudi Arabia

Location

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor of Physical Therapy

Study Record Dates

• First Submitted: November 14, 2025
• First Posted: November 18, 2025
• Study Start: December 1, 2025
• Primary Completion: February 1, 2026
• Study Completion: March 1, 2026
• Last Updated: March 10, 2026

Record last verified: 2025-11

Data Sharing

• IPD Sharing: Will share

Locations

SA (1)