Effect of Sunflower Seed Consumption on Blood Cholesterol Levels in Adults

NCT07231367 | Completed

• 1 other identifier: SUNSEED-CHOL
• Study Type: interventional
• Target: 28
• Locations: 1 country
• Sites: 1

Brief Summary

This study evaluates the effect of daily consumption of sunflower seeds on blood cholesterol levels in adult participants. Participants were randomly assigned to consume a specified amount of sunflower seeds for a defined period, and their blood cholesterol and lipid profile were measured before and after the intervention. The study aims to determine whether sunflower seeds can contribute to improving cardiovascular health by lowering cholesterol. Adult men and women meeting the eligibility criteria were included in the study. The findings may help inform dietary recommendations for managing cholesterol and promoting heart health.

Conditions

Hypercholesterolemia

Keywords

Sunflower seeds; Hypercholesterolemia; Cholesterol; Phytochemicals

Outcome Measures

Primary Outcomes (1)

• Change in Total Cholesterol

  Total serum cholesterol measured using standard enzymatic methods at baseline and at the end of the 45 days sunflower seed supplementation period.

  Baseline and 45 days after intervention

Secondary Outcomes (1)

• LDL Cholesterol

  Baseline and 45 days after intervention

Study Arms (2)

Control

NO INTERVENTION

Participants continued their usual diet without consuming sunflower seeds. Blood cholesterol and lipid profiles were measured at baseline and at the end of the study period.

Diseased Group

EXPERIMENTAL

Participants consumed a defined daily portion of sunflower seeds for the duration of the study. Blood samples were collected at baseline and after the intervention to measure total cholesterol, LDL-C, HDL-C, triglycerides, and other lipid parameters. Dietary intake and adherence to the intervention were monitored throughout the study period

Dietary Supplement: Sunflower Seed Supplementation

Interventions

Sunflower Seed Supplementation DIETARY_SUPPLEMENT

Participants consumed sunflower seeds daily for 45 days

Diseased Group

Eligibility Criteria

• Age: 40 Years - 50 Years
• Sex: male
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Participants included males aged between 40 and 50 years, with serum cholesterol levels exceeding 200 mg/dL, and shared the same socioeconomic status.

You may not qualify if:

• The participants were excluded based on different physiological factors, such as active smokers, alcoholics, chronic disease patients, people having extremely low or high BMI, people suffering from psychological disorders or familial hypercholesterolemia, people who belong to a high-income group, and people having doubts or confusion while following instructions

Sponsors & Collaborators

• University of Faisalabad: lead

Study Sites (1)

University of Agriculture, Faisalabad

Faisalābad, Punjab Province, 38000, Pakistan

Location

MeSH Terms

Conditions

Hypercholesterolemia

Condition Hierarchy (Ancestors)

Hyperlipidemias; Dyslipidemias; Lipid Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Lecturer

Study Record Dates

• First Submitted: November 13, 2025
• First Posted: November 17, 2025
• Study Start: July 5, 2023
• Primary Completion: August 20, 2023
• Study Completion: August 20, 2023
• Last Updated: November 17, 2025

Record last verified: 2025-11

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)