Study of the Rate of Progression of Cerebral Ischemia in Afro-Caribbeans

NCT07230925 | Not Yet Recruiting

• 1 other identifier: PAP_RIPH2_2025/03
• Study Type: observational
• Target: 135
• Locations: 1 country
• Sites: 1

Brief Summary

To compare the progression of cerebral ischemia from HF in Afro-Caribbean patients admitted to the CHUG to that of patients from Nantes included in the national ETIS registry.

Conditions

Ischemic Stroke; Cerebral Ischemia; Endovascular Treatments

Keywords

Cerebrovascular accident; Cerebral Blood Flow

Outcome Measures

Primary Outcomes (1)

• progression of cerebral ischemia of IC in Afro-Caribbean patients admitted to the CHUG with that of patients from Nantes included in the national register ETIS

  Compare the progression of cerebral ischemia of IC in Afro-Caribbean patients admitted to the CHUG with that of patients from Nantes included in the national register ETIS

  baseline, day 1,2,3,4 an day 90

Secondary Outcomes (3)

• Characterizing the profile of Afro-Caribbean patients

  baseline

• Characterizing the profile of Afro-Caribbean patients

  baseline

• Characterizing the profile of Afro-Caribbean

  at the end of the suty

Study Arms (2)

Patients residing in Guadeloupe

Patients residing in Guadeloupe

Other: No Interventions

Patients residing in Nantes

Patients residing in Nantes

Other: No Interventions

Interventions

No Interventions OTHER

No interventions

Patients residing in Guadeloupe; Patients residing in Nantes

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

patients with a diagnosis of stroke from LVO identified by medical imaging

You may qualify if:

• Patients aged 18 and over, admitted for IC due to LVO verified by medical imaging and hospitalized in neurology.
• Patients residing in Guadeloupe
• Afro-Caribbean patients: of African ancestry.
• Patients affiliated to a social security scheme or equivalent

You may not qualify if:

• Patients under 18 years old
• Non-resident patients in Guadeloupe
• Protected persons (articles L1121-5, L1121-6 and L121-8 of the Public Health Code): pregnant or breastfeeding women, persons deprived of their liberty, under guardianship or curatorship)
• Withdrawal of consent during the study
• Patients not affiliated to a social security or equivalent scheme

Sponsors & Collaborators

• Centre Hospitalier Universitaire de la Guadeloupe: lead

Study Sites (1)

Centre Hospitalier Universitaire de la Guadeloupe

Pointe-à-Pitre, Guadeloupe, 97159, Guadeloupe

Location

Biospecimen

Retention: SAMPLES WITH DNA

blood sample

MeSH Terms

Conditions

Ischemic Stroke; Brain Ischemia; Stroke

Condition Hierarchy (Ancestors)

Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases

Study Officials

• Donald ACCROMBESSI, Doctor

  CHU de la Guadeloupe

  PRINCIPAL INVESTIGATOR

• Valérie BASSIEN CASPA, PHD

  CHU de la Guadeloupe

  STUDY CHAIR

Central Study Contacts

Valérie HAMONY-SOTER

CONTACT

+590590934686; valerie.soter@chu-guadeloupe.fr

Eunice NUBRET

CONTACT

eunice.nubret@chu-guadeloupe.fr

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 14, 2025
• First Posted: November 17, 2025
• Study Start: January 1, 2026
• Primary Completion (Estimated): January 1, 2028
• Study Completion (Estimated): January 1, 2028
• Last Updated: November 17, 2025

Record last verified: 2025-10

Data Sharing

• IPD Sharing: Will not share

Locations

GU (1)