NCT07226804

Brief Summary

To observe the outcomes of nsPFA therapy to treat benign thyroid nodules.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
30

participants targeted

Target at below P25 for all trials

Timeline
51mo left

Started Nov 2025

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress12%
Nov 2025Aug 2030

First Submitted

Initial submission to the registry

November 7, 2025

Completed
3 days until next milestone

First Posted

Study publicly available on registry

November 10, 2025

Completed
4 days until next milestone

Study Start

First participant enrolled

November 14, 2025

Completed
2.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 31, 2028

Expected
2 years until next milestone

Study Completion

Last participant's last visit for all outcomes

August 31, 2030

Last Updated

June 1, 2026

Status Verified

May 1, 2026

Enrollment Period

2.8 years

First QC Date

November 7, 2025

Last Update Submit

May 29, 2026

Conditions

Thyroid NodulesPulsed Field Ablation

Outcome Measures

Primary Outcomes (1)

  • Quality-of-life Questionnaire

    Through study completion; an average of 1 year

Interventions

QuestionnaireOTHER

patient-reported outcomes questionnaire

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

MD Anderson Cancer Center

You may not qualify if:

  • Age \<18
  • Patients considered unsuitable for nsPFA by the treating physician

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

MD Anderson Cancer Center

Houston, Texas, 77030, United States

RECRUITING

Related Links

MeSH Terms

Conditions

Thyroid Nodule

Interventions

Surveys and Questionnaires

Condition Hierarchy (Ancestors)

Thyroid NeoplasmsEndocrine Gland NeoplasmsNeoplasms by SiteNeoplasmsHead and Neck NeoplasmsEndocrine System DiseasesThyroid Diseases

Intervention Hierarchy (Ancestors)

Data CollectionEpidemiologic MethodsInvestigative TechniquesHealth Care Evaluation MechanismsQuality of Health CareHealth Care Quality, Access, and EvaluationPublic HealthEnvironment and Public Health

Study Officials

  • Victoria E Banuchi, MD

    M.D. Anderson Cancer Center

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Victoria E Banuchi, MD

CONTACT

346-217-8668vebanuchi@mdanderson.org

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 7, 2025

First Posted

November 10, 2025

Study Start

November 14, 2025

Primary Completion (Estimated)

August 31, 2028

Study Completion (Estimated)

August 31, 2030

Last Updated

June 1, 2026

Record last verified: 2026-05

Locations

US(1)