The Lateral, Anterior, Medial (LAM) Femoral Cutaneous Block: A Case Series Harborview Medical Center, Seattle, WA

NCT07221903 | Recruiting

• 1 other identifier: STUDY00023101
• Study Type: observational
• Target: 10
• Locations: 1 country
• Sites: 1

Brief Summary

Skin donor sites in patients undergoing split-thickness skin grafting surgeries can be very painful postoperatively. This site is most often the anterolateral thigh, the pain at which location can traditionally be covered by a fascia iliaca nerve block, although that comes with the disadvantage of losing motor functions in the femoral nerve distribution. The LAM nerve block, which is relatively new, aims to provide analgesia in the distribution of the lateral and anterior femoral cutaneous nerves. In short, this nerve block would decrease the sensation of the anterolateral thigh area without affecting the motor function of the leg. Investigators aim to study the consistency and coverage size of sensation changes by mapping out the area after the block in each patient.

Conditions

Regional Anesthesia; Burn; Skin Grafting

Outcome Measures

Primary Outcomes (1)

• Area of sensory change after nerve block

  20 min after nerve block placement

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients 18 years or older who are undergoing skin grafting surgeries

You may qualify if:

• years or older
• Scheduled surgery for STSG w/ donor site coming from thigh
• Care team requests LAM nerve block
• Anticipated postop pain in the cutaneous areas of anterior and lateral thigh

You may not qualify if:

• Inability to communicate sensation or motor changes in their body
• Preexisting sensory or motor deficits in the femoral nerve distribution
• Contraindication to the medication used or a peripheral nerve block, such as allergy to amide local anesthetics, severe liver dysfunction, injection site infection etc
• Pregnancy
• Prisoners
• Non-English Speaking/reading
• Surgeries with anticipated or actual duration of 6 hours or longer
• TBSA 20% or greater
• Severe distracting injuries/polytrauma (e.g., large or significant bone fractures)

Sponsors & Collaborators

• University of Washington: lead

Study Sites (1)

Harborview Medical Center

Seattle, Washington, 98104, United States

RECRUITING

MeSH Terms

Conditions

Burns

Condition Hierarchy (Ancestors)

Wounds and Injuries

Study Officials

• Dorothy Wang, MD, MHA

  University of Washington

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Adrienne James

CONTACT

206-744-4634; ajames1@uw.edu

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Acting Assistant Professor, Department of Anesthesiology and Pain Medicine

Study Record Dates

• First Submitted: October 24, 2025
• First Posted: October 28, 2025
• Study Start: October 22, 2025
• Primary Completion (Estimated): December 31, 2026
• Study Completion (Estimated): December 31, 2026
• Last Updated: November 4, 2025

Record last verified: 2025-10

Locations

US (1)