NCT06295224

Brief Summary

In this study, the investigators aimed to evaluate the effect of ultrasound-guided anterior iliac block which was performed preoperatively. Anterior iliac bone harvesting is associated with severe postoperative pain. As several fascial plane blocks were defined to provide analgesia, their effects are debatable and requires high volumes of local anesthetic considering the regional anesthesia technique used for the main surgical procedure.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
16

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Jan 2024

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2024

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

February 19, 2024

Completed
15 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 5, 2024

Completed
1 day until next milestone

First Posted

Study publicly available on registry

March 6, 2024

Completed
4 days until next milestone

Study Completion

Last participant's last visit for all outcomes

March 10, 2024

Completed
Last Updated

March 6, 2025

Status Verified

March 1, 2025

Enrollment Period

2 months

First QC Date

February 19, 2024

Last Update Submit

March 3, 2025

Conditions

Regional Anesthesia

Keywords

Anterior Iliac BlockAnterior Iliac Crest Bone Harvesting

Outcome Measures

Primary Outcomes (1)

  • Morphine consumption

    Morphine consumption with patient controlled analgesia device

    postoperative 1st hour, 6th hour, 12th hour and 24th hour

Secondary Outcomes (1)

  • NRS score

    postoperative 1st hour, 6th hour, 12th hour and 24th hour

Study Arms (1)

Anterior Iliac Block

Patients who were performed anterior iliac block with ultrasound guidance with 10-20 mL 0.25% bupivacaine.

Eligibility Criteria

Age18 Years - 70 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients who underwent anterior iliac graft harvesting and were performed anterior iliac block at Kocaeli University Faculty of Medicine between January 2021 and December 2023 will be included in the study.

You may qualify if:

  • ASA-1, ASA-2 and ASA-3 patients
  • Female/male

You may not qualify if:

  • Anticoagulant drug use
  • Known allergy to the medications to be used
  • Infection in the area where the needle will be inserted
  • Missing data

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Kocaeli Universty

Kocaeli, Turkey (Türkiye)

Location

Related Publications (8)

  • Morgan SJ, Jeray KJ, Saliman LH, Miller HJ, Williams AE, Tanner SL, Smith WR, Broderick JS. Continuous infusion of local anesthetic at iliac crest bone-graft sites for postoperative pain relief. A randomized, double-blind study. J Bone Joint Surg Am. 2006 Dec;88(12):2606-12. doi: 10.2106/JBJS.E.00984.

    PMID: 17142410BACKGROUND

  • Black ND, Malhas L, Jin R, Bhatia A, Chan VWS, Chin KJ. The analgesic efficacy of the transversalis fascia plane block in iliac crest bone graft harvesting: a randomized controlled trial. Korean J Anesthesiol. 2019 Aug;72(4):336-343. doi: 10.4097/kja.d.18.00352. Epub 2019 Mar 19.

    PMID: 30886131BACKGROUND

  • Shin SR, Tornetta P 3rd. Donor Site Morbidity After Anterior Iliac Bone Graft Harvesting. J Orthop Trauma. 2016 Jun;30(6):340-3. doi: 10.1097/BOT.0000000000000551.

    PMID: 27218470BACKGROUND

  • Sondekoppam RV, Ip V, Johnston DF, Uppal V, Johnson M, Ganapathy S, Tsui BCH. Ultrasound-guided lateral-medial transmuscular quadratus lumborum block for analgesia following anterior iliac crest bone graft harvesting: a clinical and anatomical study. Can J Anaesth. 2018 Feb;65(2):178-187. doi: 10.1007/s12630-017-1021-y. Epub 2017 Nov 21.

    PMID: 29164530BACKGROUND

  • Gundes H, Kilickan L, Gurkan Y, Sarlak A, Toker K. Short- and long-term effects of regional application of morphine and bupivacaine on the iliac crest donor site. Acta Orthop Belg. 2000 Oct;66(4):341-4.

    PMID: 11103484BACKGROUND

  • Chin KJ, McDonnell JG, Carvalho B, Sharkey A, Pawa A, Gadsden J. Essentials of Our Current Understanding: Abdominal Wall Blocks. Reg Anesth Pain Med. 2017 Mar/Apr;42(2):133-183. doi: 10.1097/AAP.0000000000000545.

    PMID: 28085788BACKGROUND

  • Ouaki J, Dadure C, Bringuier S, Raux O, Rochette A, Captier G, Capdevila X. Continuous infusion of ropivacaine: an optimal postoperative analgesia regimen for iliac crest bone graft in children. Paediatr Anaesth. 2009 Sep;19(9):887-91. doi: 10.1111/j.1460-9592.2009.03095.x.

    PMID: 19691695BACKGROUND

  • Yorukoglu HU, Cesur S, Izgin Avci I, GoK A, Aksu C, Selek O, Kus A. Retrospective evaluation of postoperative analgesia efficacy of a new technique in anterior iliac crest bone graft harvesting: anterior iliac block. BMC Anesthesiol. 2024 Nov 29;24(1):443. doi: 10.1186/s12871-024-02829-7.

    PMID: 39609729DERIVED

Study Officials

  • Hadi Ufuk Yörükoğlu

    Kocaeli University, Department of Anesthesiology and Reanimation

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
principal investigator

Study Record Dates

First Submitted

February 19, 2024

First Posted

March 6, 2024

Study Start

January 1, 2024

Primary Completion

March 5, 2024

Study Completion

March 10, 2024

Last Updated

March 6, 2025

Record last verified: 2025-03

Data Sharing

IPD Sharing
Will not share

Locations

TU(1)