Multi-Ingredient Preworkout Supplement on Peak Torque and Muscle Activation During Fatigue

NCT07217210 | Completed

• 1 other identifier: #HS22-0139
• Study Type: interventional
• Target: 13
• Locations: 1 country
• Sites: 1

Brief Summary

The primary purpose of the present study was to examine the acute effects of a MIPS product on peak torque production of the leg extensors during a fatiguing isokinetic protocol involving isometric, concentric, and eccentric muscle actions. In addition, we investigated the effects of the MIPS supplement on EMG amplitude and median power frequency (MDF) responses from the vastus lateralis, rectus femoris, and vastus medi-alis muscles.

Conditions

Healthy Adult Male

Keywords

isometric; concentric; eccentric; leg extensors; quadriceps; electromyography

Outcome Measures

Primary Outcomes (1)

• Peak torque

  Isometric, concentric, and eccentric.

  Two days.

Secondary Outcomes (1)

• EMG responses.

  60 minutes per visit over the course of two visits (each separated by one week).

Study Arms (2)

Supplement group

EXPERIMENTAL

Multi-ingredient preworkout supplement

Dietary Supplement: Multi-ingredient preworkout supplement

Placebo group

PLACEBO COMPARATOR

Microcystalline cellulose

Dietary Supplement: Multi-ingredient preworkout supplement

Interventions

Multi-ingredient preworkout supplement DIETARY_SUPPLEMENT

Experimental supplement.

Placebo group; Supplement group

Eligibility Criteria

• Age: 19 Years - 29 Years
• Sex: male
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Male, 19-29 years of age, one year of resistance training experience

You may not qualify if:

• Subjects were eligible to participate if they did not report: 1) cardiovascular disease, metabolic, renal, hepatic, or musculoskeletal disorders; 2) use of any medications; 3) use of nutritional supplements; 4) habitual use of caffeine (≥ 1 caffeinated beverage per day); or 5) participation in another clinical trial or investigation of another nutritional product within 30 days of screening/enrollment.

Sponsors & Collaborators

• Northern Illinois University: lead

Study Sites (1)

Northern Illinois University

DeKalb, Illinois, 60115, United States

Location

Study Officials

• Clayton Camic, PHD

  Northern Illinois University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Purpose: OTHER
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: Within-subjects, placebo-controlled, crossover design

Study Record Dates

• First Submitted: October 13, 2025
• First Posted: October 15, 2025
• Study Start: November 15, 2021
• Primary Completion: March 1, 2022
• Study Completion: April 1, 2022
• Last Updated: October 15, 2025

Record last verified: 2025-10

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)