NCT07216118

Brief Summary

The goal of this clinical trial is to pilot test different strategies to address health related social needs (HRSN) experienced by adolescent and young adult patients with type 2 diabetes and their families. The main questions it aims to answer are:

  • How feasible are the strategies?
  • How acceptable are the strategies?
  • How reliably and consistently can the strategies be implemented? Participants will: Attend regularly scheduled diabetes clinic visits. Complete surveys and interviews. Be connected to community resources and organizations to help address HRSN.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
104

participants targeted

Target at P50-P75 for not_applicable

Timeline
26mo left

Started Apr 2026

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress2%
Apr 2026Jul 2028

First Submitted

Initial submission to the registry

October 9, 2025

Completed
5 days until next milestone

First Posted

Study publicly available on registry

October 14, 2025

Completed
6 months until next milestone

Study Start

First participant enrolled

April 21, 2026

Completed
1.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2028

Expected
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2028

Last Updated

April 27, 2026

Status Verified

April 1, 2026

Enrollment Period

1.9 years

First QC Date

October 9, 2025

Last Update Submit

April 22, 2026

Conditions

Outcome Measures

Primary Outcomes (6)

  • Acceptability of Intervention: Health-Related Social Needs Screener

    4-item Acceptability of Intervention Measure; completed by all adolescents and caregivers. Questions are specific to acceptability of the screening questionnaire used to assess health-related social needs, with responses ranging from completely disagree to completely agree (5-point scale). A mean of 4 or higher indicates acceptability.

    at baseline clinic visit

  • Acceptability of Intervention: Tailored Approach to Address Health-Related Social Needs

    4-item Acceptability of Intervention Measure; completed by adolescents and caregivers assigned to arms using a tailored approach (not universal empowerment). Questions are specific to acceptability of the tailored approach used to address health-related social needs, with responses ranging from completely disagree to completely agree (5-point scale). A mean of 4 or higher indicates acceptability.

    1-week after baseline; 3 months

  • Acceptability of Intervention: Universal Empowerment Approach to Address Health-Related Social Needs

    4-item Acceptability of Intervention Measure; completed by adolescents and caregivers assigned to arms using a universal empowerment approach (not tailored approach). Questions are specific to acceptability of the universal empowerment approach used to address health-related social needs, with responses ranging from completely disagree to completely agree (5-point scale). A mean of 4 or higher indicates acceptability.

    at baseline visit; 1-week after baseline; 3 months

  • Acceptability of Intervention: Text Messages to Address Health-Related Social Needs

    4-item Acceptability of Intervention Measure; completed by adolescents and caregivers assigned to arms using text messages without community health workers to support resource connection. Questions are specific to acceptability of the text messages without community health worker approach used to address health-related social needs, with responses ranging from completely disagree to completely agree (5-point scale). A mean of 4 or higher indicates acceptability.

    3 months

  • Acceptability of Intervention: Community Health Workers to Address Health-Related Social Needs

    4-item Acceptability of Intervention Measure; completed by adolescents and caregivers assigned to arms using text messages with community health workers to support resource connection. Questions are specific to acceptability of community health workers in addition to text messages to address health-related social needs, with responses ranging from completely disagree to completely agree (5-point scale). A mean of 4 or higher indicates acceptability.

    3 months

  • Fidelity of Intervention

    Investigator developed survey around receipt of intervention components including resources requested and used, community health worker interactions, and text message receipt; completed by adolescents and caregivers in all arms. Frequency and types of resources used, as well as community organizations with which respondents interacted will be reported. Frequency and duration of contact with community health workers will be reported for those assigned to arms using community health workers.

    1-week after baseline; 3 months; 6 months

Secondary Outcomes (5)

  • Health-related social needs: Food Insecurity

    Baseline, 3 months, 6 months

  • Health-related social needs: Housing Insecurity

    Baseline, 3 months, 6 months

  • Health-related social needs: Transportation Insecurity

    Baseline, 3 months, 6 months

  • Hemoglobin A1C

    Baseline, 3 months, 6 months

  • Body Mass Index

    Baseline, 3 months, 6 months

Other Outcomes (9)

  • Physical activity

    Baseline, 3 months, 6 months

  • Health Literacy

    Baseline, 3 months, 6 months

  • Mood

    Baseline, 3 months, 6 months

  • +6 more other outcomes

Study Arms (4)

Tailored Resources and Text Messages

EXPERIMENTAL

Tailored Resources AND Text Messages: Tailored Resources: Participants will be offered resource lists and warm referrals specific to health-related social needs (HRSN) on a screener. Their clinical team will be sent screener results and asked to talk about and address HRSN at the visit without additional guidance. Participants will be offered physical resources related to disclosed HRSN (e.g., food box for food insecurity). Text Messages: Participants will receive text messages once per month for 3 months. Messages will state that community-based resources to address HRSN are available if needed, with a link to opt-in to resource lists and warm referral links. Messages will include contact information for the study and clinical teams for optional HRSN discussion. Community Health Worker will not be assigned.

Behavioral: Tailored ResourcesBehavioral: Text Messages

Tailored Resources and Community Health Worker

EXPERIMENTAL

Tailored Resources AND Community Health Worker (CHW): Tailored Resources: Participants will be offered resource lists and warm referrals specific to health-related social needs (HRSN) on a screener. Their clinical team will be sent screener results and asked to talk about and address HRSN at the visit without additional guidance. Participants will be offered physical resources related to disclosed HRSN. CHW: Participants will be assigned a trained CHW to support connection with resources to address HRSN.

Behavioral: Tailored ResourcesBehavioral: Community Health Workers (CHW)

Universal Empowerment and Text Messages

EXPERIMENTAL

Assigned to Universal Empowerment AND Text Messages: Universal Empowerment: Regardless of disclosed health-related social needs (HRSN), participants will be offered physical resources and the opportunity to meet with a social worker. In place of screening results, the clinical team will be sent a message requesting that, when seeing the patient in clinic, they use the provided, easily accessible empowering script about HRSN. Text Messages: Participants randomized to text message will receive text messages once per month for 3 months. Messages will state that community-based resources to address HRSN are available if needed, with a link to opt-in to resource lists and warm referral links. Messages will include contact information for the study and clinical teams for optional HRSN discussion. Community Health Worker will not be assigned to participants.

Behavioral: Universal EmpowermentBehavioral: Text Messages

Universal Empowerment and Community Health Worker

EXPERIMENTAL

Universal Empowerment AND Community Health Worker (CHW): Universal Empowerment: Regardless of disclosed health-related social needs (HRSN), participants will be offered physical resources and the opportunity to meet with a social worker. In place of screening results, the clinical team will be sent a message requesting that, when seeing the patient in clinic, they use the provided, easily accessible empowering script about HRSN. CHW: Participants will be assigned a trained CHW to support connection with resources to address HRSN.

Behavioral: Universal EmpowermentBehavioral: Community Health Workers (CHW)

Interventions

Participants will be offered resource lists and warm referrals specific to health-related social needs (HRSN) on a screener. Their clinical team will be sent screener results and asked to talk about and address HRSN at the visit without additional guidance. Participants will be offered physical resources related to disclosed HRSN (e.g., food box for food insecurity).

Also known as: Tailored
Tailored Resources and Community Health WorkerTailored Resources and Text Messages

Regardless of disclosed health-related social needs (HRSN), participants will be offered resource lists and warm referral links for food, housing, and transportation needs. At clinic visit, all will be offered physical resources and the opportunity to meet with a social worker. In place of screening results, the clinical team will be sent a message requesting that, when seeing the patient in clinic, they use the provided, easily accessible empowering script about HRSN.

Also known as: Universal
Universal Empowerment and Community Health WorkerUniversal Empowerment and Text Messages
Text MessagesBEHAVIORAL

Participants will receive text messages once per month for 3 months. Messages will state that community-based resources to address health-related social needs (HRSN) are available if needed, with a link to opt-in to resource lists and warm referral links. Messages will include contact information for the study and clinical teams for optional HRSN discussion. Community Health Worker will not be assigned.

Also known as: Text Only
Tailored Resources and Text MessagesUniversal Empowerment and Text Messages

Participants will be assigned a trained CHW to support connection with resources to address HRSN.

Also known as: CHW
Tailored Resources and Community Health WorkerUniversal Empowerment and Community Health Worker

Eligibility Criteria

Age13 Years+
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Age 13 to 22 years old
  • known diagnosis of type 2 diabetes
  • followed clinically at UPMC Children's Hospital of Pittsburgh
  • able to provide assent/consent
  • Adult (18 years or older) identifying as a primary caretaker of an adolescent or young adult with type 2 diabetes
  • Has an adolescent/young adult who agrees to participate in the study
  • able to provide consent

You may not qualify if:

  • Inability to complete study questionnaires in English

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

UPMC Children's Hospital of Pittsburgh

Pittsburgh, Pennsylvania, 15224, United States

RECRUITING

MeSH Terms

Conditions

Diabetes Mellitus, Type 2

Interventions

Community Health Workers

Condition Hierarchy (Ancestors)

Diabetes MellitusGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System Diseases

Intervention Hierarchy (Ancestors)

Allied Health PersonnelHealth PersonnelHealth Care Facilities Workforce and Services

Study Officials

  • Mary Ellen Vajravelu, MD MSHP

    University of Pittsburgh

    PRINCIPAL INVESTIGATOR
  • Maya I Ragavan, MD MPH MS

    University of Pittsburgh

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Mary Ellen Vajravelu, MD MSHP

CONTACT

Maya I Ragavan, MD MPH MS

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
FACTORIAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor

Study Record Dates

First Submitted

October 9, 2025

First Posted

October 14, 2025

Study Start

April 21, 2026

Primary Completion (Estimated)

April 1, 2028

Study Completion (Estimated)

July 1, 2028

Last Updated

April 27, 2026

Record last verified: 2026-04

Data Sharing

IPD Sharing
Will share

We will share de-identified individual-participant level (IPD) data including demographic and health-related social needs data from participant self-report, clinical laboratory and body mass index data upon reasonable request from investigators.

Shared Documents
STUDY PROTOCOL, SAP, ICF
Time Frame
Beginning 3 months and ending 3 years after the publication of results.
Access Criteria
Investigators must submit a proposal in writing that describes planned analyses, and a data sharing agreement with the University of Pittsburgh must be signed.

Locations