NCT07213011

Brief Summary

Static stretching and self-myofascial release are commonly used techniques to improve joint mobility, primarily through mechanisms such as reduced tissue stiffness, increased stretch tolerance, and warming effects. Emerging evidence suggests that these interventions may also elicit remote effects, improving range of motion in body segments distant from the site of application. These non-local adaptations are thought to occur via mechanisms such as myofascial force transmission, systemic increases in stretch tolerance, or global neuromuscular responses. This phenomenon may have important clinical implications, particularly in scenarios where direct treatment of a target area is limited due to pain, injury, or immobilization. Therefore, this study explores the potential for local and remote effects of static stretching and self-myofascial release applied to the right posterolateral neck region. Specifically, this study investigates whether targeted cervical interventions can acutely improve not only cervical range of motion but also hip flexion range of motion on the ipsilateral (right) side. The proposed mechanisms include reductions in tissue stiffness, increased stretch tolerance and pressure pain threshold, and the transmission of mechanical forces along myofascial chains, particularly the "superficial back line," which anatomically connects the cervical region to the posterior lower limb. The primary aim of this study was to compare the acute effects of neck static stretching and neck self-myofascial release using a massage roller on both local (cervical) and remote (right hip) ROM.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
30

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started May 2025

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 14, 2025

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 28, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 28, 2025

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

October 1, 2025

Completed
7 days until next milestone

First Posted

Study publicly available on registry

October 8, 2025

Completed
Last Updated

November 19, 2025

Status Verified

November 1, 2025

Enrollment Period

3 months

First QC Date

October 1, 2025

Last Update Submit

November 15, 2025

Conditions

Keywords

stretchmassage rollercervicalmobilityremote effects

Outcome Measures

Primary Outcomes (3)

  • Range Of Motion

    Right hip flexion range of motion (ROM) was assessed using the Active Straight Leg Raise test. Participants lay in a supine position with the test knee fully extended and the ankle dorsiflexed, a setup intended to specifically assess hamstring extensibility. Hip flexion was measured in degrees using the GYKO inertial measurement unit. Cervical ROM was evaluated with participants seated and secured to the chair at the chest level using inelastic straps to limit trunk movement. The GYKO accelerometer was positioned on the forehead via a head strap and recorded active cervical movements in flexion, extension, right and left rotation, and right and left inclination. The investigators collected three ROM measurements for each movement (hip flexion, cervical flexion/extension, right and left cervical rotation, right and left cervical inclination) and for each time point (T0 and T1), then used the average of the three measurements for statistical analysis.

    During each condition (SS, SMR, CC), hip and cervical ROM was collected at two time-points: upon arrival (T0) and immediately following the assigned condition (T1).

  • Tissue Hardness

    Tissue hardness (TH) nwas assessed using a portable TH meter (NEUTONE TDM-N1; TRY-ALL Corp., Chiba, Japan). For cervical TH assessment, the spinous process of C7 served as the anatomical landmark. Measurements were taken at two locations, positioned 2 cm lateral to the right and left of the C7 spinous process. Assessment of TH in the right knee flexors was conducted using the ischial tuberosity as the proximal reference point and the popliteal fossa as the distal landmark. Measurements were obtained at two specific sites located in the proximal third of the posterior thigh: a lateral site corresponding to the biceps femoris and a medial site corresponding to the semitendinosus/semimembranosus muscle complex. All TH measurements were performed with participants in a prone position on a medical examination bed. Participants were instructed to remain relaxed throughout the procedure. For each time point (T0 and T1), three consecutive measurements were taken per anatomical site.

    During each condition (SS, SMR, CC), cervical and hamstring TH was collected at two time-points: upon arrival (T0) and immediately following the assigned condition (T1).

  • Pain Pressure Threshold

    Pain pressure threshold (PPT) was measured using a portable digital algometer (FPX 25 Pain Tester, Wagner Instruments, CT, USA). Participant positioning and the anatomical testing sites were identical to those used for the TH assessments. The algometer probe was applied perpendicularly to the muscle fibers, and pressure was manually increased at a constant rate of 1 kg·s-¹ by the same trained investigator to ensure consistency. Participants were instructed to verbally indicate "stop" at the point where the sensation first transitioned from pressure to pain. The corresponding value displayed on the algometer at that moment, expressed in kg·cm-², was recorded as the PPT. The investigators collected three PPT measurements for each anatomical site and time point (T0 and T1), then used the average of the three measurements for statistical analysis.

    During each condition (SS, SMR, CC), cervical and hamstring PPT was collected at two time-points: upon arrival (T0) and immediately following the assigned condition (T1).

Study Arms (3)

Static stretching

EXPERIMENTAL

The neck static stretching protocol consisted of four sets of 45 seconds each, with 45-second rest intervals between sets, resulting in a total intervention time of three minutes. Participants remained seated in an upright position and executed the stretch by gently inclining the head in an anterolateral direction, forward and to the left, while using the contralateral (left) hand to assist the movement. This positioning was intended to specifically target and elongate the right posterolateral neck musculature.

Other: Neck static stretching

Self-myofascial release

EXPERIMENTAL

For the neck self-myofascial release intervention, a Theraband® Roller Massager (The Hygenic Corporation, Akron, OH, USA) was utilized. This device features a rigid plastic core encased in high-density foam with a grooved surface, designed to facilitate both superficial and deeper tissue stimulation. The self-myofascial release protocol consisted of four sets, each comprising 45 rhythmic rolling movements performed at a standardized cadence of one roll per second, totaling three minutes of intervention time. The rolling tempo was regulated using a metronome application (Tempo Lite, version 5.0.8; Apple App Store). A 45-second rest interval was provided between sets. While seated, participants self-administered the rolling technique to the right posterolateral region of the neck, ensuring coverage of the largest possible surface area. To optimize tissue elongation, the head was maintained in a gently inclined anterolateral position, forward and to the left, throughout the intervention.

Other: Neck self-myofascial release

Control

NO INTERVENTION

In the control condition (CC), participants remained seated quietly on a chair for a period of 6 minutes, matching the duration of the static stretching and self-myofascial release protocols, but without performing any active intervention, between the baseline and post assessments.

Interventions

The neck static stretching (SS) protocol consisted of four sets, each lasting 45 seconds, interspersed with 45-second recovery periods (total intervention time: 3 minutes). While seated on a chair, participants performed the stretch by gently inclining the head forward and to the left in an antero-lateral direction and assisting the movement with the contralateral (left) hand to specifically elongate the right posterolateral neck region.

Static stretching

For the self-myofascial release (SMR) intervention, a Theraband® roller massager was employed. The device consists of a rigid plastic core surrounded by dense foam, designed with a grooved surface to facilitate both superficial and deeper tissue stimulation. The SMR protocol comprised four sets (total intervention time: 3 minutes), during which participants executed 45 rhythmic rolling movements per set at a cadence of one roll per second. The tempo was standardized using a metronome application. For the SMR condition, the protocol included 45-second recovery intervals between sets. Participants, seated on a chair, were instructed to perform self-administered rolling on the right posterolateral neck region using the massage roller and to cover the largest possible area of the posterolateral neck region during the rolling, with the head gently inclined forward and to the left in an antero-lateral direction.

Self-myofascial release

Eligibility Criteria

Age18 Years - 55 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Healthy male and female participants aged 18 or older.

You may not qualify if:

  • orthopedic or neurological disorders;
  • current and recent injuries or damage to the upper and lower limbs.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Palermo

Palermo, Italy

Location

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
BASIC SCIENCE
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor in the Department of Psychology, Education Sciences and Human Movement

Study Record Dates

First Submitted

October 1, 2025

First Posted

October 8, 2025

Study Start

May 14, 2025

Primary Completion

July 28, 2025

Study Completion

July 28, 2025

Last Updated

November 19, 2025

Record last verified: 2025-11

Locations