Mineral Bone Disorder in Dialysis

NCT07212972 | Completed FDA Device

• 1 other identifier: TZ-B
• Study Type: observational
• Target: 167
• Locations: 1 country
• Sites: 1

Brief Summary

This study was conducted with 167 dialysis patients at Erciyes University Faculty of Medicine, Department of Internal Medicine, Department of Nephrology, and Dialysis Unit, with the approval of the Ethics Committee of Erciyes University Medical Faculty (date: 25.09.2019, no: 2019/673). Patients aged ≥18 years, undergoing dialysis treatment, and having available data on serum calcium, phosphorus, parathormone, albumin, hemoglobin, blood urea nitrogen (BUN), creatinine, and dialysate calcium levels within the last six months were included in the study.

Conditions

Chronic Kidney Failure; Chronic Kidney Disease-Mineral and Bone Disorder; Dialysis; Hemodialysis

Outcome Measures

Primary Outcomes (1)

• Blood values

  Serum levels of calcium, phosphorus, parathyroid hormone, albumin, hemoglobin, BUN, creatinine, and dialysate calcium

  At the enrollment

Study Arms (1)

dialysis

167 patients diagnosed with CKD and undergoing HD or PD were included in the study

Other: Hemodialysis or peritoneal Dialysis

Interventions

Hemodialysis or peritoneal Dialysis OTHER

Hemodialysis or peritoneal Dialysis

dialysis

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

This study was performed with dialysis patients from Erciyes University Hospital, Faculty of Medicine, Department of Internal Medicine, and Department of Nephrology, and Dialysis Unit

You may qualify if:

• Age ≥ 18 years,
• Diagnosed with chronic kidney disease (CKD) and undergoing dialysis treatment (hemodialysis or peritoneal dialysis)
• Availability of laboratory results within the last 6 months: serum calcium, phosphorus, parathormone, albumin, hemoglobin, blood urea nitrogen (BUN), creatinine, and dialysate calcium
• Patient consent to participate

You may not qualify if:

• Age \< 18 years
• Patients not on dialysis treatment
• Missing or incomplete laboratory data
• History of malignancy, acute infection, or other systemic diseases interfering with mineral and bone metabolism
• Patients who did not provide consent or could not complete the questionnaire

Sponsors & Collaborators

• Çanakkale Onsekiz Mart University: lead

Study Sites (1)

Erciyes University Hospital, Faculty of Medicine, Department of Internal Medicine, and Department of Nephrology, and Dialysis Unit

Kayseri, Turkey (Türkiye)

Location

Biospecimen

Retention: SAMPLES WITH DNA

blood

MeSH Terms

Conditions

Kidney Failure, Chronic; Chronic Kidney Disease-Mineral and Bone Disorder

Interventions

Renal Dialysis; Peritoneal Dialysis

Condition Hierarchy (Ancestors)

Renal Insufficiency, Chronic; Renal Insufficiency; Kidney Diseases; Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Male Urogenital Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Rickets; Bone Diseases, Metabolic; Bone Diseases; Musculoskeletal Diseases; Metabolic Diseases; Nutritional and Metabolic Diseases; Calcium Metabolism Disorders; Vitamin D Deficiency; Avitaminosis; Deficiency Diseases; Malnutrition; Nutrition Disorders; Hyperparathyroidism, Secondary; Hyperparathyroidism; Parathyroid Diseases; Endocrine System Diseases

Intervention Hierarchy (Ancestors)

Renal Replacement Therapy; Therapeutics; Sorption Detoxification

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Dr.

Study Record Dates

• First Submitted: October 2, 2025
• First Posted: October 8, 2025
• Study Start: September 25, 2019
• Primary Completion: April 15, 2020
• Study Completion: June 20, 2020
• Last Updated: October 8, 2025

Record last verified: 2022-05

Locations

TU (1)