Prognostic Importance of Physical Activity in Geriatric Patients With Acute Coronary Syndrome

NCT07203924 | Completed

• 1 other identifier: 2024/192 (BU Ethics No)
• Study Type: observational
• Target: 207
• Locations: 1 country
• Sites: 1

Brief Summary

This observational study evaluated the relationship between physical activity level and prognosis in geriatric patients admitted to the emergency department with acute coronary syndrome (ACS). A total of 207 patients aged 65 years and older were included. Physical activity level was assessed using the International Physical Activity Questionnaire-Short Form (IPAQ-SF) and compared with clinical outcomes and risk scores (TIMI, HEART, SVEAT). Results showed that patients with higher physical activity levels had lower rates of major adverse cardiac events (MACE) and mortality, as well as lower risk scores. The findings suggest that physical activity is an independent protective factor that improves prognosis in older patients with ACS.

Conditions

Acute Coronary Syndromes; Geriatric Patients; Physical Activity Levels

Keywords

Acute Coronary Syndrome; TIMI; HEART; SVEAT; Physical Activity

Outcome Measures

Primary Outcomes (1)

• Major Adverse Cardiac Events (MACE)

  Occurrence of major adverse cardiac events (MACE) including STEMI, NSTEMI, unstable angina, or cardiovascular mortality.

  Within 30 days after emergency department admission

Secondary Outcomes (5)

• Physical Activity Score (IPAQ-SF)

  At baseline (hospital admission, emergency department evaluation)

• TIMI Risk Score

  At baseline (emergency department evaluation)

• HEART Risk Score

  At baseline (emergency department evaluation)

• SVEAT Risk Score

  At baseline (emergency department evaluation)

• All-cause Mortality

  Within 30 days after admission

Study Arms (1)

Geriatric ACS Patients

This cohort consists of 207 patients aged 65 years and older who presented to the emergency department with acute coronary syndrome (ACS). No intervention was performed. Physical activity levels were assessed using the International Physical Activity Questionnaire-Short Form (IPAQ-SF), and outcomes were compared with major adverse cardiac events (MACE), mortality, and risk scores (TIMI, HEART, SVEAT).

Eligibility Criteria

• Age: 65 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The study population consisted of 207 geriatric patients aged 65 years and older who were admitted to the emergency department with a diagnosis of acute coronary syndrome (ACS)

You may qualify if:

• Age ≥ 65 years
• Admission to the emergency department with a diagnosis of acute coronary syndrome (ACS)
• Ability to complete the International Physical Activity Questionnaire-Short Form (IPAQ-SF)

You may not qualify if:

• Age \< 65 years
• Patients without ACS diagnosis
• Patients unable to complete the IPAQ-SF questionnaire (e.g., due to severe cognitive impairment or communication problems)

Sponsors & Collaborators

• Balikesir University: lead

Study Sites (1)

Balıkesir University Faculty of Sport Sciences / Department of Coaching Education

Balıkesir, Balıkesir, 10145, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Acute Coronary Syndrome; Motor Activity

Condition Hierarchy (Ancestors)

Myocardial Ischemia; Heart Diseases; Cardiovascular Diseases; Vascular Diseases; Behavior

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: September 12, 2025
• First Posted: October 2, 2025
• Study Start: December 4, 2024
• Primary Completion: September 1, 2025
• Study Completion: September 11, 2025
• Last Updated: October 6, 2025

Record last verified: 2025-10

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)