Evaluation of the Role of Brain Natriuretic Peptide in Acute Coronary Syndrome .

NCT06734416 | Not Yet Recruiting

• 1 other identifier: BNP IN ACS
• Study Type: observational
• Target: 100
• Locations: 0 countries
• Sites: N/A

Brief Summary

The measurements of the natriuretic peptide are useful and beneficial for risk stratification irrespective of the cause during admission time or during hospital stay course. the aim of the study is to Assessment of the role of Brain natriuretic peptide in diagnosis of acute coronary syndrome . Evaluation of the relation of Brain natriuretic peptide to the severity and occurrence of complications in acute coronary syndrome .

Conditions

Acute Coronary Syndromes

Keywords

Brain natriuretic peptide

Outcome Measures

Primary Outcomes (1)

• Brain natriuretic peptide level in blood

  level of Brain natriuretic peptide in acute coronary syndrome patients.

  baseline

Study Arms (2)

group 1

patients with Acute Coronary Syndrome , this group will be sub classified into: Non-ST-elevation myocardial infarction (NSTEMI) ST-elevation myocardial infarction (STEMI) Unstable angina

group 2

apparently healthy patients will be included in this study as a control group for comparison

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

patients with acute coronary syndrome.

You may qualify if:

• patients with acute coronary syndrome.

You may not qualify if:

• Patients with previous MI
• Eection fraction (EF) less than 30%
• Patients having cardiomyopathy
• Patients having renal, liver, malignant, infectious, or inflammatory diseases .

Sponsors & Collaborators

• Assiut University: lead

Related Publications (2)

• Volterrani M, Iellamo F, Senni M, Piepoli MF. Therapeutic options of Angiotensin Receptor Neprilysin inhibitors (ARNis) in chronic heart failure with reduced ejection fraction: Beyond RAAS and sympathetic nervous system inhibition. Int J Cardiol. 2017 Jan 1;226:132-135. doi: 10.1016/j.ijcard.2016.04.180. Epub 2016 May 7.

  PMID: 27184730 BACKGROUND

• Mukoyama M, Nakao K, Hosoda K, Suga S, Saito Y, Ogawa Y, Shirakami G, Jougasaki M, Obata K, Yasue H, et al. Brain natriuretic peptide as a novel cardiac hormone in humans. Evidence for an exquisite dual natriuretic peptide system, atrial natriuretic peptide and brain natriuretic peptide. J Clin Invest. 1991 Apr;87(4):1402-12. doi: 10.1172/JCI115146.

  PMID: 1849149 BACKGROUND

MeSH Terms

Conditions

Acute Coronary Syndrome

Condition Hierarchy (Ancestors)

Myocardial Ischemia; Heart Diseases; Cardiovascular Diseases; Vascular Diseases

Central Study Contacts

Mennat-Allah Gamal kamel Mohamed, resident doctor

CONTACT

+201098695613; mennagamalkamel@gmail.com

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: resident doctor at Assiut University hospital

Study Record Dates

• First Submitted: December 11, 2024
• First Posted: December 16, 2024
• Study Start: January 1, 2025
• Primary Completion: January 1, 2026
• Study Completion: March 1, 2026
• Last Updated: December 16, 2024

Record last verified: 2024-12