Analysis of Variability in the Management of Respiratory Infections in Hospitalized Patients Under 2 Years of Age

NCT07202585 | Completed

• 1 other identifier: Variability PMS
• Study Type: observational
• Target: 127
• Locations: 1 country
• Sites: 1

Brief Summary

Medical practice variability refers to differences in treatment and clinical outcomes that cannot be solely explained by patient characteristics or medical conditions. This variability can lead to inconsistent outcomes, especially in complex environments like pediatric inpatient wards. Standardization of care protocols is proposed as a way to reduce this inconsistency.

Conditions

Bronchiolitis; Bronchiolitis Acute Viral

Keywords

Acute Lower Respiratory Infections (ALRI); Pediatric Respiratory Infections; Clinical Variability; Propensity Score Matching

Outcome Measures

Primary Outcomes (1)

• Variability in the treatment:Length of Hospital Stay

  * Definition: Total number of full calendar days from admission to pediatric ward until medical discharge. * Measurement: Recorded in patient's medical record. Calculated as discharge date - admission date. * Type of Variable: Continuous (days). * Analysis: Mean/median days compared between groups after Propensity Score Matching.

  2 years

Secondary Outcomes (1)

• Explore Clinical outcomes

  2 years

Eligibility Criteria

• Age: 1 Month - 24 Months
• Sex: all
• Age Groups: Child (0-17)
• Sampling Method: Non-Probability Sample

Study Population

Children under 2 years hospitalized with LARI in general pediatric wards during the winter months (June-September) of 2025 and 2026 in Buenos Aires

You may qualify if:

• Children under 2 years hospitalized with LARI in general pediatric wards during the winter months (June-September) of 2025 and 2026 in Buenos Aires

You may not qualify if:

• Intensive care admission on entry Presence of comorbidities: congenital heart disease. Chronic respiratory conditions, neuromuscular diseases, immunodeficiencies,.
• Prolonged previous hospitalizations for unrelated causes Severe disabilities influencing hospitalization duration.

Sponsors & Collaborators

• Hospital General de Niños Pedro de Elizalde: lead

Study Sites (1)

HGNPE

Buenos Aires, 1270, Argentina

Location

Related Publications (1)

• Kane LT, Fang T, Galetta MS, Goyal DKC, Nicholson KJ, Kepler CK, Vaccaro AR, Schroeder GD. Propensity Score Matching: A Statistical Method. Clin Spine Surg. 2020 Apr;33(3):120-122. doi: 10.1097/BSD.0000000000000932.

  PMID: 31913173 BACKGROUND

MeSH Terms

Conditions

Bronchiolitis

Condition Hierarchy (Ancestors)

Bronchitis; Respiratory Tract Infections; Infections; Bronchial Diseases; Respiratory Tract Diseases; Lung Diseases, Obstructive; Lung Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: August 6, 2025
• First Posted: October 2, 2025
• Study Start: May 1, 2025
• Primary Completion: December 1, 2025
• Study Completion: December 1, 2025
• Last Updated: April 2, 2026

Record last verified: 2026-03

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL, SAP, ICF, CSR, ANALYTIC CODE
• Time Frame: 3 years

Locations

AR (1)