Perfusion Index and End Diastolic Velocity Ratios as Predictors of Supraclavicular Block Success in Vascular Access Surgery

NCT07197281 | Not Yet Recruiting

• 1 other identifier: PI and EDV as Predictors
• Study Type: observational
• Target: 50
• Locations: 0 countries
• Sites: N/A

Brief Summary

This is a prospective observational study investigating the correlation between Perfusion Index (PI) ratio and End Diastolic Velocity (EDV) ratio as early predictors of successful supraclavicular brachial plexus block (SCBPB) in patients undergoing superficialization surgery of the upper limb.

Conditions

End Diastolic Velocity; Perfusion Index

Keywords

End Diastolic Velocity; brachial plexus block; Perfusion Index

Outcome Measures

Primary Outcomes (2)

• Change in Perfusion Index ratio

  Change in Perfusion Index ratio at 15 minutes after supraclavicular brachial plexus block in predicting successful block

  15 minutes

• Change in End Diastolic Velocity ratio

  Change in End Diastolic Velocity ratio at 15 minutes after supraclavicular brachial plexus block in predicting successful block

  15 minutes

Study Arms (1)

adult patients scheduled for elective superficialization surgery of the upper limb

Participants are adult patients aged 18-65 years, both male and female, classified as ASA II-VI, and scheduled for elective superficialization procedures (mainly AV fistula superficialization).

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Participants are adult patients aged 18-65 years, both male and female, classified as ASA II-VI, and scheduled for elective superficialization procedures (mainly AV fistula superficialization). Patients must be capable of understanding and signing informed consent. Excluded are patients with contraindications to nerve block such as coagulopathy, local infection, allergy to local anesthetics, severe vascular disease, morbid obesity (BMI \>35), severe neurological or psychiatric impairment, or those taking vasopressors or beta-blockers that could alter vascular reactivity.

You may qualify if:

• Adults aged 18-65 years
• Both genders
• ASA II-VI classification
• Undergoing elective upper limb superficialization surgery (e.g., AVF superficialization)
• Provided written informed consent

You may not qualify if:

• Patient refusal
• Coagulopathy or bleeding disorders
• Local infection at injection site
• Allergy to local anesthetics
• Use of vasopressors or beta-blockers
• Severe peripheral vascular disease
• Morbid obesity (BMI \> 35)
• Severe neurological or psychiatric disorders

Sponsors & Collaborators

• Assiut University: lead

Related Publications (1)

• Abdelnasser A, Abdelhamid B, Elsonbaty A, Hasanin A, Rady A. Predicting successful supraclavicular brachial plexus block using pulse oximeter perfusion index. Br J Anaesth. 2017 Aug 1;119(2):276-280. doi: 10.1093/bja/aex166.

  PMID: 28854539 BACKGROUND

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: resident at the Anesthesia, Intensive Care, and Pain Management department

Study Record Dates

• First Submitted: September 20, 2025
• First Posted: September 29, 2025
• Study Start: May 1, 2026
• Primary Completion (Estimated): October 30, 2027
• Study Completion (Estimated): December 30, 2027
• Last Updated: September 29, 2025

Record last verified: 2025-09

Data Sharing

• IPD Sharing: Will not share