NCT07194213

Brief Summary

Prevelance of hypercalciurea in children with sterorid dependent nephrotic syndrome

Trial Health

55
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
50

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Jan 2024

Typical duration for all trials

Geographic Reach
1 country

2 active sites

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2024

Completed
1.7 years until next milestone

First Submitted

Initial submission to the registry

September 19, 2025

Completed
7 days until next milestone

First Posted

Study publicly available on registry

September 26, 2025

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2026

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2026

Completed
Last Updated

September 26, 2025

Status Verified

September 1, 2025

Enrollment Period

2 years

First QC Date

September 19, 2025

Last Update Submit

September 19, 2025

Conditions

Steroid-Dependent Nephrotic Syndrome; HypercalciuriaSteroid Dependent Nephrotic SyndromeHupercalciurea

Keywords

ChildrenPediatrics

Outcome Measures

Primary Outcomes (1)

  • Prevalence of hypercalciurea

    At enrollment

Study Arms (1)

Children with steroid dependent nephrotic syndrome

Participants will undergo urine analysis to measure calcium excretion in order to assess the prevalence of hypercalciuria. No experimental treatment will be given.

Eligibility Criteria

Age2 Years - 16 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)
Sampling MethodNon-Probability Sample
Study Population

Children diagnosed with steroid-dependent nephrotic syndrome who are being followed up at the pediatric nephrology clinic.

You may qualify if:

  • \- Age between 2 and 16 years.
  • Diagnosis of steroid-dependent nephrotic syndrome (according to standard clinical criteria).
  • Currently in remission or relapse while on steroid therapy.

You may not qualify if:

  • \- Children with congenital or secondary nephrotic syndrome.
  • Presence of other chronic kidney diseases.
  • Use of medications that affect calcium metabolism (other than steroids).
  • Children with systemic diseases affecting bone or mineral metabolism.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Sohag university hospital

Sohag, 82524, Egypt

Location

Sohag university hospital

Sohag, Egypt

Location

MeSH Terms

Conditions

Nephrotic SyndromeHypercalciuria

Condition Hierarchy (Ancestors)

NephrosisKidney DiseasesUrologic DiseasesFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesMale Urogenital DiseasesUrological ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
CROSS SECTIONAL
Target Duration
1 Day
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Ahmed ewees

Study Record Dates

First Submitted

September 19, 2025

First Posted

September 26, 2025

Study Start

January 1, 2024

Primary Completion

January 1, 2026

Study Completion

April 1, 2026

Last Updated

September 26, 2025

Record last verified: 2025-09

Data Sharing

IPD Sharing
Will not share

De-identified individual participant data (IPD) that underlie the results of the study will be made available upon reasonable request from the principal investigator, after publication of the main results.

Locations

EG(2)