Promoting Aging and Thriving With HIV

NCT07192419 | Enrolling By Invitation

• 2 other identifiers: 27767K76AG064545-01
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 2

Brief Summary

The pilot is an intervention of a geriatric assessment and management tool (PATH) in outpatient HIV clinics.

Conditions

Geriatric; Geriatric Assessment; HIV; HIV - Human Immunodeficiency Virus

Outcome Measures

Primary Outcomes (3)

• Feasibility: recruitment and retention

  Feasibility will be measured by tracking the number of participants approached, enrolled, retained, observations by study team throughout study.

  Recruitment day one, throughout the study to final assessment six months post baseline of the last participant.

• Feasibility: patient/provider experience

  Feasibility will be measured by qualitative Interviews with patients and providers. Interview questions will be used to derive personal anecdotes of the patient/provider experience pertaining to the feasibility of the study.

  After completing final outcomes at the 6 month assessment (or earlier if difficulty with recruitment/retention) patients and providers will be invited to participate in an optional qualitative interview.

• Acceptability; General attitudes, perception of intervention

  Acceptability will be measured by qualitative Interviews with patients and providers. Interview questions will be used to derive personal anecdotes of the patient/provider general attitudes, perception of intervention.

  After completing final outcomes at the 6 month assessment (or as needed if difficulty with recruitment/retention) patients and providers will be invited to participate in an optional qualitative interview.

Secondary Outcomes (3)

• Impact of PATH Outcomes: measured by identification of geriatric conditions

  Geriatric Conditions will be measured through chart review at baseline, 3month, and 6 month assessments to determine overall change from baseline.

• Impact of PATH Outcomes: measured by addressing unmet needs.

  Unmet needs will be measured through survey questions and chart review at baseline, 3month, and 6 month assessments.

• Quality of life as measured by Medical Outcomes 36-Item Short Form Survey (SF-36)

  Quality of life will be measures at baseline, 3 months and 6 months post baseline assessments.

Study Arms (2)

Usual Care

NO INTERVENTION

Usual care participants will receive HIV and aging information before their regular medical appointment.

PATH

EXPERIMENTAL

The PATH group will undergo an aging assessment using the PATH toolkit before their regular medical appointment.

Behavioral: Promoting Aging and Thriving with HIV (PATH)-Implementation of a Tailored Geriatric Assessment and Management Strategy for HIV Care Settings

Interventions

Promoting Aging and Thriving with HIV (PATH)-Implementation of a Tailored Geriatric Assessment and Management Strategy for HIV Care Settings BEHAVIORAL

For the intervention arm, participants will be sent geriatric assessment questions through the patient portal in advance of a routine HIV appointment. If the participant is unable to complete the questions in advance, they will be done with the help of a research coordinator to go through on the day of appointment. Every attempt will be made to ensure the assessment can be done in advance of the appointment, however the study team will allow for visits after the regular appointment as in which case the provider will receive results after the patient has left clinic. The provider will receive the PATH assessment responses and a discussion guide with suggested initial management steps. The provider ultimately determines with the participant when and if they will address concerns identified (that visit or future visit) based on participant priorities. The patient participant will also receive a copy of their screening results.

PATH

Eligibility Criteria

• Age: 50 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age 50 or older
• Receive HIV care (at least 1 visit at the same site within the past 12 months) from either Eskenazi Health IDC or LifeCare clinics,
• Able to provide informed consent

You may not qualify if:

• Patients who are long-term nursing home residents
• Patients who are receiving geriatric care services, however will liberalize this criteria if difficulty with recruitment

Sponsors & Collaborators

• National Institute on Aging (NIA): collaborator
• Indiana University: lead

Study Sites (2)

Eskenazi Health

Indianapolis, Indiana, 46202, United States

Location

IU Health LifeCare

Indianapolis, Indiana, 46202, United States

Location

MeSH Terms

Conditions

Acquired Immunodeficiency Syndrome

Interventions

Seroconversion

Condition Hierarchy (Ancestors)

HIV Infections; Blood-Borne Infections; Communicable Diseases; Infections; Sexually Transmitted Diseases, Viral; Sexually Transmitted Diseases; Lentivirus Infections; Retroviridae Infections; RNA Virus Infections; Virus Diseases; Slow Virus Diseases; Genital Diseases; Urogenital Diseases; Immunologic Deficiency Syndromes; Immune System Diseases

Intervention Hierarchy (Ancestors)

Immune System Phenomena

Study Officials

• Meredith Greene, MD

  Indiana University School of Medicine, and Regenstrief Institute; IU Center for Aging Research

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: SCREENING
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor

Study Record Dates

• First Submitted: August 27, 2025
• First Posted: September 25, 2025
• Study Start: October 17, 2025
• Primary Completion (Estimated): September 1, 2026
• Study Completion (Estimated): September 1, 2026
• Last Updated: December 19, 2025

Record last verified: 2025-12

Data Sharing

• IPD Sharing: Will not share

Locations

US (2)