Guaranteed Income to Boost HIV Care Continuity and Suppression Post-Jail Release
GI-BOOST
2 other identifiers
interventional
33
1 country
1
Brief Summary
The goal of this clinical trial is to understand the implementation requirements and potential health impacts of a guaranteed income (GI) intervention targeting people living with HIV with criminal legal involvement (PWH-CLI). The main questions it aims to answer are:
- How acceptable is a GI intervention, and its intervention components, among PWH-CLI participants and stakeholders?
- How feasible is a GI intervention for PWH-CLI? What are the implementation barriers and opportunities for this intervention?
- What is the preliminary efficacy of the GI intervention on improving HIV care outcomes for PWH-CLI? Researches will compare study engagement and study outcomes across three randomization arms (A: receive full GI amount as one lump sum payment; B: receive full GI amount split over nine monthly installments; C: participant chooses whether to receive GI as lump sum payment or monthly installments). HIV care outcomes will be compared against a retrospective cohort of PWH-CLI patients as historical controls. Participants will:
- Be randomized to receive GI intervention as a lump sum payment or monthly installment (over nine months) or choose their preference.
- Complete 3 surveys throughout study follow up to assess experience with the intervention, experience with social services and benefits programs, experience with the criminal legal system, and HIV care outcomes.
- Be interviewed by the research team to further understand the experience with the intervention.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started Dec 2025
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
August 4, 2025
CompletedFirst Posted
Study publicly available on registry
August 11, 2025
CompletedStudy Start
First participant enrolled
December 1, 2025
CompletedPrimary Completion
Last participant's last visit for primary outcome
February 25, 2027
ExpectedStudy Completion
Last participant's last visit for all outcomes
February 25, 2027
March 13, 2026
March 1, 2026
1.2 years
August 4, 2025
March 10, 2026
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
HIV viral suppression
Percent of participants (total and by randomization arm) that are HIV virally suppressed at 9 months
From enrollment to end of the intervention at 9 months
Secondary Outcomes (2)
Linkage to HIV care
From enrollment to one month after enrollment
Retention in HIV care
From enrollment to end of intervention at 9 months
Study Arms (3)
Lump sum
EXPERIMENTALParticipants receive the full guaranteed income amount ($6,750) as one lump sum payment at the beginning of the study.
Monthly Installments
EXPERIMENTALParticipants receive the guaranteed income intervention split into 9-monthly installments of $750/month
Choice
EXPERIMENTALParticipants choose which method of Guaranteed Income disbursement they will receive (either lump sum or monthly installments).
Interventions
Participants receive guaranteed income (GI) to the amount of $6,750 as a one-time lump sum payment.
Participants receive guaranteed income (GI) to the total amount of $6,750 as 9-monthly installments of $750 per month
Participants choose which method of guaranteed income disbursement they will receive (lump sum or monthly installment)
Eligibility Criteria
You may qualify if:
- years of age or older,
- Living with an HIV diagnosis
- Have a recent incarceration in the San Francisco County Jail (within three months of study enrollment)
- Qualify as very low income (for example, currently experiencing homelessness or having an income less than 30% of the area median income).
- English literate.
You may not qualify if:
- Individuals with an active psychosis who are not on treatment
- individuals who do not have a social security number or individual tax ID number
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
University of California, San Francisco
San Francisco, California, 94158, United States
Related Publications (5)
Delevry D, Le QA. Effect of Treatment Preference in Randomized Controlled Trials: Systematic Review of the Literature and Meta-Analysis. Patient. 2019 Dec;12(6):593-609. doi: 10.1007/s40271-019-00379-6.
PMID: 31372909BACKGROUNDWest S, Castro A. Impact of Guaranteed Income on Health, Finances, and Agency: Findings from the Stockton Randomized Controlled Trial. J Urban Health. 2023 Apr;100(2):227-244. doi: 10.1007/s11524-023-00723-0. Epub 2023 Apr 10.
PMID: 37037977BACKGROUNDMoher M, Erickson M, Black P, Price M, Fraser C, Norman WV, Guillemi S, Pick N, Elwood Martin R. Improving Post-Release Care Engagement for People Living with HIV Involved in the Criminal Justice System: A Systematic Review. AIDS Behav. 2022 May;26(5):1607-1617. doi: 10.1007/s10461-021-03513-4. Epub 2021 Oct 27.
PMID: 34705154BACKGROUNDIroh PA, Mayo H, Nijhawan AE. The HIV Care Cascade Before, During, and After Incarceration: A Systematic Review and Data Synthesis. Am J Public Health. 2015 Jul;105(7):e5-16. doi: 10.2105/AJPH.2015.302635. Epub 2015 May 14.
PMID: 25973818BACKGROUNDBadowski ME, Patel M. Evaluation of Immunologic and Virologic Function in Reincarcerated Patients Living With HIV or AIDS. J Correct Health Care. 2022 Jun;28(3):203-206. doi: 10.1089/jchc.20.07.0055. Epub 2022 Apr 21.
PMID: 35447035BACKGROUND
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Paul D Wesson, PhD
University of California, San Francisco
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- OTHER
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
August 4, 2025
First Posted
August 11, 2025
Study Start
December 1, 2025
Primary Completion (Estimated)
February 25, 2027
Study Completion (Estimated)
February 25, 2027
Last Updated
March 13, 2026
Record last verified: 2026-03
Data Sharing
- IPD Sharing
- Will not share
Given the small projected sample size for this pilot study (n=33) and the vulnerable nature of the study population (people living with HIV with recent criminal legal involvement), we do not have plans to share IPD in order to protect participant anonymity.