Postoperative SpO₂/FiO₂ in Obese and Non-Obese Patients: Role of STOP-BANG

NCT07188649 | Not Yet Recruiting

• 1 other identifier: hulusi tez
• Study Type: observational
• Target: 64
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study is to evaluate the effect of the Reverse Trendelenburg position on oxygenation (SpO₂/FiO₂ ratio) in the early postoperative period in patients undergoing laparoscopic surgery. In our study, obesity is considered as a comparative subgroup in terms of variability of this effect; additionally, the STOP-BANG score, which measures the risk of obstructive sleep apnea syndrome, is examined as an auxiliary indicator.

Conditions

Oxygen Deficiency

Outcome Measures

Primary Outcomes (1)

• oxygen level

  SpO₂/FiO₂ ratio

  4 months

Study Arms (2)

obese

BMI ≥ 35

Behavioral: oxygen deficiency

control

BMI \< 35

Behavioral: oxygen deficiency

Interventions

oxygen deficiency BEHAVIORAL

The aim of this study is to evaluate the effect of the Reverse Trendelenburg position on oxygenation (SpO₂/FiO₂ ratio) in the early postoperative period in patients undergoing laparoscopic surgery. In our study, obesity is considered as a comparative subgroup in terms of variability of this effect; additionally, the STOP-BANG score, which measures the risk of obstructive sleep apnea syndrome, is examined as an auxiliary indicator.

control; obese

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Adults over 18, ASA I-III patients, patients who give consent to participate, patients undergoing elective laparoscopic surgery (obesity surgery, cholecystectomy, umbilical hernia, etc.)

You may qualify if:

• Patients over 18 years old
• Patients who give consent to participate in the study
• Patients who underwent elective laparoscopic cholecystectomy in Reverse Trendelenburg (30 degrees) position
• ASA I-III patients
• Patients with operation time \< 3 hours

You may not qualify if:

• Patients under 18 years old
• Patients who did not give consent
• Patients with asthma, COPD, or known respiratory disease
• Patients whose procedure could not be completed or who had missing data
• Patients with general anesthesia duration \< 90 minutes will not be included

Sponsors & Collaborators

• Istinye University: lead

Study Sites (1)

Istinye Üniversity

Istanbul, Merkez Mahallesi, 34250, Turkey (Türkiye)

Location

Related Publications (2)

• Michael Dunham C, Hileman BM, Hutchinson AE, Antonaccio T, Chance EA, Huang GS, Szmaj G, Calabro K, Bishop C, Schrickel TT. Evaluation of operating room reverse Trendelenburg positioning and its effect on postoperative hypoxemia, aspiration, and length of stay: a retrospective study of consecutive patients. Perioper Med (Lond). 2017 Aug 22;6:10. doi: 10.1186/s13741-017-0067-2. eCollection 2017.

  PMID: 28852473 RESULT

• 5. Pirenne S, Hans G, Leloup von Edelsberg S, Joris J. STOP-BANG but not BMI predicts postoperative obstructive apnea and hypoxemia after laparoscopic upper-abdominal surgery. University of Liège, Department of Anaesthesiology & Intensive Care, Belgium.

  RESULT

MeSH Terms

Conditions

Hypoxia

Condition Hierarchy (Ancestors)

Signs and Symptoms, Respiratory; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Central Study Contacts

ilke dolgun

CONTACT

+905555485632; ilkeser2004@gmail.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assoc. prof

Study Record Dates

• First Submitted: September 16, 2025
• First Posted: September 23, 2025
• Study Start: September 25, 2025
• Primary Completion: January 25, 2026
• Study Completion: February 15, 2026
• Last Updated: September 23, 2025

Record last verified: 2025-09

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)