NCT07182825

Brief Summary

Nonspecific low back pain is a common musculoskeletal problem that also affects many young adults, including university students. It can negatively impact academic performance, daily life, and overall well-being. Research shows that stabilization exercises targeting the lumbar multifidus muscle play an important role in rehabilitation, but it is unclear whether modified versions of these exercises may provide additional benefits. This study will investigate a simple modification of the traditional "bird-dog" exercise, called the "Multifidus Lift Exercise." In this version, participants maintain the contralateral knee about 10 cm above the ground while in a four-point kneeling position. This adjustment is expected to increase multifidus activation and improve back endurance. University students aged 18-25 with nonspecific low back pain will participate in a 6-week supervised program, performing the exercise twice weekly. A healthy control group without low back pain will also be included. The main outcome will be back extensor muscle endurance (Biering-Sørensen Test). In participants with back pain, pain intensity (Visual Analog Scale) and functional disability (Oswestry Disability Index) will also be measured. The study aims to determine whether this low-cost, practical, and time-efficient exercise can improve muscle endurance, reduce pain, and decrease disability in young adults with low back pain. Results may provide evidence for an effective and accessible preventive and therapeutic approach in student populations.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
40

participants targeted

Target at P25-P50 for not_applicable low-back-pain

Timeline
Completed

Started Oct 2025

Shorter than P25 for not_applicable low-back-pain

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 14, 2025

Completed
5 days until next milestone

First Posted

Study publicly available on registry

September 19, 2025

Completed
12 days until next milestone

Study Start

First participant enrolled

October 1, 2025

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 31, 2026

Completed
28 days until next milestone

Study Completion

Last participant's last visit for all outcomes

February 28, 2026

Completed
Last Updated

September 19, 2025

Status Verified

September 1, 2025

Enrollment Period

4 months

First QC Date

September 14, 2025

Last Update Submit

September 14, 2025

Conditions

Keywords

Nonspecific Low Back PainMultifidus MuscleMultifidus Lift ExerciseBird-Dog Exercise (Modified)Spinal Stabilization ExerciseEndurancePainDisabilityOswestry Disability Index (ODI)Visual Analog Scale (VAS)Biering-Sørensen TestUniversity StudentsYoung AdultsHealthy Controls

Outcome Measures

Primary Outcomes (1)

  • Lumbar Extensor Muscle Endurance (Biering-Sørensen Test)

    Endurance of the lumbar extensor muscles will be assessed using the standardized Biering-Sørensen Test. Participants lie prone with the upper body unsupported beyond the table edge while the pelvis and lower limbs are stabilized. The duration (in seconds) that the participant can maintain the horizontal position without \>10° deviation is recorded.

    Baseline (pre-test) and after 6 weeks of intervention.

Secondary Outcomes (2)

  • Pain Intensity (Visual Analog Scale, VAS)

    Baseline (pre-test) and after 6 weeks of intervention.

  • Functional Disability (Oswestry Disability Index, ODI)

    Baseline (pre-test) and after 6 weeks of intervention.

Study Arms (2)

NSCLBP Students - Modified Multifidus Lift Exercise

EXPERIMENTAL

University students aged 18-25 years with nonspecific chronic low back pain. Participants will perform the supervised modified Multifidus Lift Exercise protocol, twice weekly for 6 weeks. Each session includes warm-up, exercise progression (8-15 repetitions depending on week), and cool-down. Outcomes: lumbar extensor endurance (primary), pain intensity (VAS), and functional disability (ODI).

Behavioral: Modified Multifidus Lift Exercise (MLE)

Healthy Students - Modified Multifidus Lift Exercise

EXPERIMENTAL

Healthy university students aged 18-25 years without low back pain in the past 3 months. Participants will perform the same supervised modified Multifidus Lift Exercise protocol, twice weekly for 6 weeks, with identical warm-up, exercise progression, and cool-down. Outcome: lumbar extensor endurance (Biering-Sørensen Test).

Behavioral: Modified Multifidus Lift Exercise (MLE)

Interventions

A supervised stabilization exercise protocol designed to selectively activate the lumbar multifidus muscle. In the quadruped position, the contralateral knee is maintained approximately 10 cm above the ground while the participant performs controlled trunk stabilization. Sessions are conducted twice weekly for 6 weeks, each including warm-up (5 minutes brisk walk, mobilization, hamstring stretch), the modified Multifidus Lift Exercise with progressive repetitions (weeks 1-2: 8-10, weeks 3-4: 10-12, weeks 5-6: 12-15), and cool-down (static stretches). All sessions are supervised to ensure correct form, breathing control, and safety.

Also known as: Modified Bird-Dog Exercise, Multifidus Lift
Healthy Students - Modified Multifidus Lift ExerciseNSCLBP Students - Modified Multifidus Lift Exercise

Eligibility Criteria

Age18 Years - 25 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Age between 18 and 25 years
  • Currently enrolled as a university student at Selçuk University
  • Willing to participate voluntarily and sign informed consent form
  • Medically suitable for exercise participation
  • For NSCLBP group:
  • History of nonspecific chronic low back pain within the past 3 months
  • Physician confirmation of nonspecific low back pain
  • Oswestry Disability Index (ODI) ≥ 21% (moderate disability)
  • Visual Analog Scale (VAS) score ≥ 3.5
  • For Healthy control group:
  • No history of low back pain within the past 3 months
  • Physician confirmation of no contraindications for exercise

You may not qualify if:

  • Presence of radicular pain or nerve root compression symptoms
  • History of spinal surgery
  • Neurological deficits within the past 3 months (e.g., muscle weakness, reflex loss, paresthesia)
  • Systemic infection or systemic disease affecting participation
  • Cardiovascular or pulmonary disease contraindicating exercise
  • Clinical "red flag" symptoms (e.g., saddle anesthesia, bowel/bladder incontinence, fever, known cancer)
  • Pregnancy
  • Regular use of analgesics, muscle relaxants, or anti-inflammatory medications
  • Participation in regular exercise programs in the past 3 months
  • Active involvement in sports directly affecting lumbar muscles (e.g., fitness, pilates, yoga, swimming)
  • Inability to comply with exercise sessions or study protocol

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Selçuk University, Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation

Konya, Konya, 42130, Turkey (Türkiye)

Location

Related Publications (14)

  • Yakut E, Duger T, Oksuz C, Yorukan S, Ureten K, Turan D, Frat T, Kiraz S, Krd N, Kayhan H, Yakut Y, Guler C. Validation of the Turkish version of the Oswestry Disability Index for patients with low back pain. Spine (Phila Pa 1976). 2004 Mar 1;29(5):581-5; discussion 585. doi: 10.1097/01.brs.0000113869.13209.03.

    PMID: 15129077BACKGROUND
  • Williamson A, Hoggart B. Pain: a review of three commonly used pain rating scales. J Clin Nurs. 2005 Aug;14(7):798-804. doi: 10.1111/j.1365-2702.2005.01121.x.

    PMID: 16000093BACKGROUND
  • Stevens VK, Vleeming A, Bouche KG, Mahieu NN, Vanderstraeten GG, Danneels LA. Electromyographic activity of trunk and hip muscles during stabilization exercises in four-point kneeling in healthy volunteers. Eur Spine J. 2007 May;16(5):711-8. doi: 10.1007/s00586-006-0181-1. Epub 2006 Aug 1.

    PMID: 16896840BACKGROUND
  • Smeets R, Koke A, Lin CW, Ferreira M, Demoulin C. Measures of function in low back pain/disorders: Low Back Pain Rating Scale (LBPRS), Oswestry Disability Index (ODI), Progressive Isoinertial Lifting Evaluation (PILE), Quebec Back Pain Disability Scale (QBPDS), and Roland-Morris Disability Questionnaire (RDQ). Arthritis Care Res (Hoboken). 2011 Nov;63 Suppl 11:S158-73. doi: 10.1002/acr.20542. No abstract available.

    PMID: 22588742BACKGROUND
  • Shafshak TS, Elnemr R. The Visual Analogue Scale Versus Numerical Rating Scale in Measuring Pain Severity and Predicting Disability in Low Back Pain. J Clin Rheumatol. 2021 Oct 1;27(7):282-285. doi: 10.1097/RHU.0000000000001320.

    PMID: 31985722BACKGROUND
  • Sarafadeen R, Ganiyu SO, Ibrahim AA. Effects of spinal stabilization exercise with real-time ultrasound imaging biofeedback in individuals with chronic nonspecific low back pain: a pilot study. J Exerc Rehabil. 2020 Jun 30;16(3):293-299. doi: 10.12965/jer.2040380.190. eCollection 2020 Jun.

    PMID: 32724788BACKGROUND
  • Pitcher MJ, Behm DG, Mackinnon SN. Neuromuscular fatigue during a modified biering-sorensen test in subjects with and without low back pain. J Sports Sci Med. 2007 Dec 1;6(4):549-59. eCollection 2007.

    PMID: 24149491BACKGROUND
  • Pirouzi S, Emami F, Taghizadeh S, Ghanbari A. Is Abdominal Muscle Activity Different from Lumbar Muscle Activity during Four-Point Kneeling? Iran J Med Sci. 2013 Dec;38(4):327-33.

    PMID: 24293787BACKGROUND
  • Maher C, Underwood M, Buchbinder R. Non-specific low back pain. Lancet. 2017 Feb 18;389(10070):736-747. doi: 10.1016/S0140-6736(16)30970-9. Epub 2016 Oct 11.

    PMID: 27745712BACKGROUND
  • Hawker GA, Mian S, Kendzerska T, French M. Measures of adult pain: Visual Analog Scale for Pain (VAS Pain), Numeric Rating Scale for Pain (NRS Pain), McGill Pain Questionnaire (MPQ), Short-Form McGill Pain Questionnaire (SF-MPQ), Chronic Pain Grade Scale (CPGS), Short Form-36 Bodily Pain Scale (SF-36 BPS), and Measure of Intermittent and Constant Osteoarthritis Pain (ICOAP). Arthritis Care Res (Hoboken). 2011 Nov;63 Suppl 11:S240-52. doi: 10.1002/acr.20543. No abstract available.

    PMID: 22588748BACKGROUND
  • Faul F, Erdfelder E, Lang AG, Buchner A. G*Power 3: a flexible statistical power analysis program for the social, behavioral, and biomedical sciences. Behav Res Methods. 2007 May;39(2):175-91. doi: 10.3758/bf03193146.

    PMID: 17695343BACKGROUND
  • Fairbank JC, Pynsent PB. The Oswestry Disability Index. Spine (Phila Pa 1976). 2000 Nov 15;25(22):2940-52; discussion 2952. doi: 10.1097/00007632-200011150-00017.

    PMID: 11074683BACKGROUND
  • Demoulin C, Vanderthommen M, Duysens C, Crielaard JM. Spinal muscle evaluation using the Sorensen test: a critical appraisal of the literature. Joint Bone Spine. 2006 Jan;73(1):43-50. doi: 10.1016/j.jbspin.2004.08.002.

    PMID: 16461206BACKGROUND
  • Boonstra AM, Schiphorst Preuper HR, Balk GA, Stewart RE. Cut-off points for mild, moderate, and severe pain on the visual analogue scale for pain in patients with chronic musculoskeletal pain. Pain. 2014 Dec;155(12):2545-2550. doi: 10.1016/j.pain.2014.09.014. Epub 2014 Sep 17.

    PMID: 25239073BACKGROUND

Related Links

MeSH Terms

Conditions

Low Back PainPain

Condition Hierarchy (Ancestors)

Back PainNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Central Study Contacts

Mehmet Akif Güler, PhD, PT

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Masking Details
No masking will be implemented. Both participants and investigators are aware of the intervention assignment.
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: Two parallel groups will be studied: (1) university students aged 18-25 years with nonspecific chronic low back pain, and (2) healthy controls without low back pain. Both groups will receive the same 6-week supervised modified Multifidus Lift Exercise protocol. Group allocation is based on participants' clinical status; no randomization will be performed.
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
PhD, Lecturer

Study Record Dates

First Submitted

September 14, 2025

First Posted

September 19, 2025

Study Start

October 1, 2025

Primary Completion

January 31, 2026

Study Completion

February 28, 2026

Last Updated

September 19, 2025

Record last verified: 2025-09

Locations