NCT07180550|Recruiting

Acute Effects of High-intensity Interval Aerobic and Functional Training at Different Intensities

HIIT-HIFT-FT

Evaluation of the Acute Effects of High-intensity Interval Aerobic Training, Moderate- and High-intensity Functional Training, and Moderate-intensity Functional Training

European University Miguel de Cervantes ClinicalTrials.gov

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Other study identifiers

Sponsor study identifier

PI-DOC008-HIIT-HIFT-FT

Study Type

interventional

Estimated enrollment

Locations

1 country

Sites

Timeline

Study Start

October 12, 2025

Actual (reported)

Primary Completion

January 1, 2027

Estimated

Planned date reported by the registry; this milestone is not confirmed as achieved.

Study Completion

January 31, 2027

Estimated

Planned date reported by the registry; this milestone is not confirmed as achieved.

Brief Summary

Moderate-intensity physical exercise is widely recognized for its health benefits, yet time constraints limit adherence. High-intensity interval training (HIIT) has gained popularity as a more time-efficient alternative, eliciting significant cardiovascular, respiratory, metabolic, and neuromuscular responses. More recently, functional strength exercises have been integrated into high-intensity training, leading to high-intensity functional training (HIFT) and moderate-intensity functional training (MIFT). However, the acute physiological responses to these modalities remain underexplored compared to traditional HIIT (running or cycling) and strength training. This study aims to assess and compare the acute cardiovascular, metabolic, and neuromuscular responses of HIFT, MIFT, HIIT, and traditional strength training in healthy, physically active adults to inform their potential application in special populations.

Registry Overview

Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.

Recruitment status: recruiting
Estimated enrollment: 27 participants
Study completion date: January 31, 2027
Estimated
Planned date reported by the registry; this milestone is not confirmed as achieved.
Listed locations: 1 countries · 1 sites

Trial Relationships

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Some registry-reported names shown below are not yet linked in this graph.

Study Timeline

Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.

First Submitted
September 9, 2025
Actual (reported)
First Posted
September 18, 2025
Actual (reported)
Study Start
October 12, 2025
Actual (reported)
Primary Completion
January 1, 2027
Estimated
Planned date reported by the registry; this milestone is not confirmed as achieved.
Study Completion
January 31, 2027
Estimated
Planned date reported by the registry; this milestone is not confirmed as achieved.

Last Updated: March 10, 2026
Status Verified: March 2026
Last Update Submitted: March 9, 2026

Conditions

High Intensity Functional Training High Intensity Interval Training (Cycling)High Intensity Interval Training (Running)High Intensity Traditional Strength Training

Study Arms (6)

High-intensity interval training (running)

EXPERIMENTAL

Participants will perform a high-intensity interval training based on six sets of 2-minute runs at an intensity of 90-95% of the maximal aerobic speed (MAS) on a treadmill. The recovery between each set will be 2 minutes, during which the subject will walk at an intensity of 50-60% of MAS.

Other: High-intensity interval training, running

High-intensity interval training (cycling)

EXPERIMENTAL

Participants will perform a high-intensity interval training based on six sets of 2-minute cycling will be performed at an intensity of 90-95% of the maximal heart rate on a stationary bike. The recovery between each set will be 2 minutes, during which the subject will cycle at an intensity of 50-60% of maximal heart rate.

Other: High-intensity interval training, cycling

High-intensity functional training

EXPERIMENTAL

Participants will perform a high-intensity functional training based on three sets of six repetitions will be performed at 80% of the one repetition maximum (1-RM) for six exercises. The recovery between exercises will be the minimum time required to switch from one exercise to the next, and between sets, it will be two minutes. Participants will be instructed to move the load as quickly as possible during each repetition.

Other: High-intensity functional training

Moderate-intensity functional training

EXPERIMENTAL

Participants will perform a moderate-intensity functional training based on three sets of six repetitions will be performed at 60% of the 1-RM for six exercises. The recovery between exercises will be the minimum time required to switch from one exercise to the next, and between sets, it will be two minutes. Participants will be instructed to move the load as quickly as possible during each repetition.

Other: Moderate-intensity functional training

High-intensity traditional training

EXPERIMENTAL

Participants will perform a high-intensity traditional training based on three sets of six repetitions will be performed at 80% of the 1-RM for six exercises. The recovery after each set will be two minutes of passive rest. Participants will be instructed to move the load as quickly as possible during each repetition.

Other: High intensity traditional strength training

Moderate-intensity traditional training

EXPERIMENTAL

Participants will perform a high-intensity traditional training based on three sets of six repetitions will be performed at 60% of the 1-RM for six exercises. The recovery after each set will be two minutes of passive rest. Participants will be instructed to move the load as quickly as possible during each repetition.

Other: Moderate intensity traditional strength training

Interventions

High-intensity interval training, runningOther

Six sets of 2-minute runs will be performed at an intensity of 90-95% of the maximal aerobic speed (MAS) on a treadmill. The recovery between each set will be 2 minutes, during which the subject will walk at an intensity of 50-60% of MAS.

High-intensity interval training (running)

High-intensity interval training, cyclingOther

Six sets of 2-minute cycling will be performed at an intensity of 90-95% of the maximal heart rate on a stationary bike. The recovery between each set will be 2 minutes, during which the subject will cycle at an intensity of 50-60% of maximal heart rate.

High-intensity interval training (cycling)

High-intensity functional trainingOther

Three sets of six repetitions will be performed at 80% of the one repetition-maximum (1-RM) for six exercises. The recovery between exercises will be the minimum time required to switch from one exercise to the next, and between sets, it will be two minutes. Participants will be instructed to move the load as quickly as possible during each repetition.

High-intensity functional training

Moderate-intensity functional trainingOther

Three sets of six repetitions will be performed at 60% of the 1-RM for six exercises. The recovery between exercises will be the minimum time required to switch from one exercise to the next, and between sets, it will be two minutes. Participants will be instructed to move the load as quickly as possible during each repetition.

Moderate-intensity functional training

Moderate intensity traditional strength trainingOther

Three sets of six repetitions will be performed at 60% of the 1-RM for six exercises. The recovery after each set will be two minutes of passive rest. Participants will be instructed to move the load as quickly as possible during each repetition.

Moderate-intensity traditional training

High intensity traditional strength trainingOther

Three sets of six repetitions will be performed at 80% of the 1-RM for six exercises. The recovery after each set will be two minutes of passive rest. Participants will be instructed to move the load as quickly as possible during each repetition.

High-intensity traditional training

Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.

Acute Effects of High-intensity Interval Aerobic and Functional Training at Different Intensities

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

First Submitted

First Posted

Study Start

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (6)

Other Outcomes (11)

Study Arms (6)

High-intensity interval training (running)

High-intensity interval training (cycling)

High-intensity functional training

Moderate-intensity functional training

High-intensity traditional training

Moderate-intensity traditional training

Interventions

Eligibility Criteria

You may qualify if:

You may not qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Interventions

Intervention Hierarchy (Ancestors)

Central Study Contacts

Study Design

Study Record Dates

Data Sharing

Source record

Locations

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

First Submitted

First Posted

Study Start

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (6)

Other Outcomes (11)

Study Arms (6)

High-intensity interval training (running)

High-intensity interval training (cycling)

High-intensity functional training

Moderate-intensity functional training

High-intensity traditional training

Moderate-intensity traditional training

Interventions

Eligibility Criteria

You may qualify if:

You may not qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Interventions

Intervention Hierarchy (Ancestors)

Central Study Contacts

Study Design

Study Record Dates

Data Sharing

Source record

Locations