Mobile Platform for Optimizing Wellness and Engagement in Recovery
MPOWER
2 other identifiers
interventional
50
1 country
1
Brief Summary
This pilot study addresses the urgent public health crisis of co-occurring opioid and alcohol use disorders (OUD-AUD), leading causes of mortality in the United States, by testing a scalable digital contingency management (CM) treatment among Medicaid beneficiaries. The study aims to evaluate the feasibility and acceptability of digital CM for OUD-AUD recovery, while also planning for broader implementation.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started Dec 2025
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
September 10, 2025
CompletedFirst Posted
Study publicly available on registry
September 17, 2025
CompletedStudy Start
First participant enrolled
December 8, 2025
CompletedPrimary Completion
Last participant's last visit for primary outcome
July 1, 2027
ExpectedStudy Completion
Last participant's last visit for all outcomes
July 31, 2027
May 6, 2026
December 1, 2025
1.6 years
September 10, 2025
May 1, 2026
Conditions
Keywords
Outcome Measures
Primary Outcomes (4)
Feasibility based on recruitment
Recruitment: ≥60% of participants enrolled
Recruitment period 12 months
Feasibility based on adherence
Adherence: ≥50% of app-based, biochemically-verified tests completed in the digital CM condition.
6 months (during the Dynamicare program)
Feasibility based on Retention
Retention: ≥70% of participants retained at 6 months
6 months
Acceptability of the intervention
Defined as \>70% of participants rating the intervention experience ≥ 4/5 on the Acceptability of Intervention Measure
3-month after starting program
Study Arms (2)
Digital Contingency Management (CM) Intervention Arm
EXPERIMENTALAfter participants meet eligibility and complete the DynamiCare assessment period, participants randomized to this group will receive a comprehensive digital CM platform designed to enhance OAT retention and promote abstinence from alcohol and opioids. This will include the DynamiCare Motivation Support Program.
Wellness Condition
ACTIVE COMPARATORAfter participants meet eligibility and complete the DynamiCare assessment period, those randomized to this group will receive a wellness digital platform that includes surveys, testing, and tech support.
Interventions
Participants will use a version of the app for 6-months focussed on wellness. During the 6 months this will include: random requests to do saliva drug tests, breathalyzer tests, and video selfies, complete surveys and questionnaires through the app, and receive rewards on a debit card for completing tests, surveys, and activities. Participants in this group may also earn rewards for completing study activities like tests and surveys. Additionally, participants will complete follow-up at approximately 9 months after randomization.
Participants will use a version of the app for 6-months. Participants in this group may earn rewards for completing recovery-related activities and for abstinence from drugs and alcohol. During the 6 months this will include: random saliva drug tests, breathalyzer tests, and video selfies, completing surveys and questionnaires through the app, and receiving rewards on a debit card for abstinent tests, surveys, and activities. Additionally, participants will complete follow-up at approximately 9 months after randomization.
Eligibility Criteria
You may qualify if:
- Participants must be enrolled in the Michigan Medicaid program
- Opioid agonist treatment (OAT): Participants must have initiated OAT with buprenorphine or methadone
- Participants must have an OAT prescription and Alcohol use disorder (AUD) based on self-report measure during screening
- Participants must have regular access to a working smartphone and internet connection.
- Participants must have a reliable mailing address to receive study supplies (e.g., salivary drug tests).
You may not qualify if:
- Primary Medicare Coverage: Individuals that are dual-eligible for Medicaid and Medicare and aged 65 or older, due to limited availability of Medicaid claims data for this group
- Individuals that cannot voluntarily provide informed consent themselves for any reason, including legal incompetency
- Individuals with substantial cognitive impairment that would interfere with study participation
- Individuals unable to read or understand English
- Individuals experiencing active suicidality or psychosis.
- Individuals with a planned admission to residential treatment or incarceration during the study period.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- University of Michiganlead
- DynamiCare Healthcollaborator
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)collaborator
Study Sites (1)
University of Michigan
Ann Arbor, Michigan, 48109, United States
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Lara Coughlin, PhD
University of Michigan
- PRINCIPAL INVESTIGATOR
Anne C Fernandez, PhD
University of Michigan
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Associate Professor of Psychiatry
Study Record Dates
First Submitted
September 10, 2025
First Posted
September 17, 2025
Study Start
December 8, 2025
Primary Completion (Estimated)
July 1, 2027
Study Completion (Estimated)
July 31, 2027
Last Updated
May 6, 2026
Record last verified: 2025-12
Data Sharing
- IPD Sharing
- Will share
- Shared Documents
- STUDY PROTOCOL, SAP, ICF
- Time Frame
- The research team will share data with NIAAA data archive (NIAAADA) biannually per funder requirements. The data in the NIAAADA are catalogued and made available to the general research community at the time of an associated publication or end of the award/support period, whichever comes first. Data in the NIAAADA is available indefinitely.
- Access Criteria
- Community of scientists interested in the study of alcohol use and related interventions. Additionally, data submitted to National Institute on Alcohol Abuse and Alcoholism Data Archive (NIAAADA) will be accessible by the general research community via NIAAADA.
National Institute on Alcohol Abuse and Alcoholism (NIAAA)-funded investigators conducting applicable human subjects research are expected to submit de-identified, individual-level data to this data archive. The data generated in this grant will also be presented at national or international meetings (e.g., Research Society on Alcoholism, Addiction Health Services Research, etc.) and published in a timely fashion. All final peer-reviewed manuscripts that arise from this proposal will be submitted to the digital archive in PubMed Central.