Pancreatic Disease Burden in Older Adults (1990-2040)
Global, Regional, and National Burdens of Pancreatic Cancer and Pancreatitis Among Older Adults From 1990 to 2021 With Projections to 2040: A Comprehensive and Comparative Investigation
1 other identifier
observational
723,415
0 countries
N/A
Brief Summary
Using data from the Global Burden of Disease Study 2021, the investigators analyzed age-standardized incidence, mortality, and disability-adjusted life-years (DALYs) for pancreatic cancer and pancreatitis in adults aged ≥70 years across 204 countries and territories, stratified by sex, Socio-Demographic Index (SDI), health system performance, and region. The investigators calculated estimated annual percentage changes (EAPCs), applied age-period-cohort modelling, and used Bayesian models to project future burden. Attributable burdens for key risk factors were also estimated.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jan 1990
Longer than P75 for all trials
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 1990
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 31, 2021
CompletedFirst Submitted
Initial submission to the registry
September 10, 2025
CompletedStudy Completion
Last participant's last visit for all outcomes
September 11, 2025
CompletedFirst Posted
Study publicly available on registry
September 17, 2025
CompletedSeptember 17, 2025
September 1, 2025
32 years
September 10, 2025
September 10, 2025
Conditions
Outcome Measures
Primary Outcomes (3)
Incidence
The number of new cases of a givencause during a given period in aspecified population. It is xpressed as the number of newcases in a year divided by the mid-year population size.
1990-2021
Deaths
Deaths occurring in a population during a certain time period.
1990-2021
Disability-adjusted life years (DALYs)
The sum of years lost due to premature death (YLLs) and yearslived with disability (YLDs). DALYs are also defined as years of healthy life lost.
1990-2021
Study Arms (2)
Pancreatic Cancer
Pancreatitis
Interventions
Eligibility Criteria
The study population consisted of patients aged 70 years or older who were diagnosed with either pancreatic cancer or pancreatitis between 1990 and 2021. Individuals under the age of 70 were excluded from participation. Additionally, those with comorbid non-pancreatic diseases were also excluded to minimize potential confounding effects and to maintain a focus on conditions specifically related to the pancreas.
You may qualify if:
- Diagnosis with pancreatic cancer or pancreatitis
- Diagnosis in 1990 through 2021
- Age 70+ years
You may not qualify if:
- Age \<70 years
- Other non-pancreatic diseases
Contact the study team to confirm eligibility.
Sponsors & Collaborators
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Prof. Dr.
Study Record Dates
First Submitted
September 10, 2025
First Posted
September 17, 2025
Study Start
January 1, 1990
Primary Completion
December 31, 2021
Study Completion
September 11, 2025
Last Updated
September 17, 2025
Record last verified: 2025-09