Effects of Low Level Laser Therapy on Wrist Flexors Spasticity and Hand Functions in Patients With Stroke

NCT07171788 | Not Yet Recruiting

• 1 other identifier: P.T.REC/012/005969
• Study Type: interventional
• Target: 40
• Locations: 0 countries
• Sites: N/A

Brief Summary

this study will be conducted to investigate the effect of low level laser therapy (LLLT) on wrist flexors spasticity and hand functions in patient with stroke

Conditions

Stroke

Keywords

low level laser therapy; wrist flexor spasticity; hand function; stroke

Outcome Measures

Primary Outcomes (3)

• spasticity

  Modified ashworth scale will be used to assess spaticity according the following criteria,0: No increase in muscle tone 1. Slight increase in muscle tone, with a catch and release or minimal resistance at the end of the range of motion when an affected part(s) is moved in flexion or extension 1+: Slight increase in muscle tone, manifested as a catch, followed by minimal resistance through the remainder (less than half) of the range of motion 2. A marked increase in muscle tone throughout most of the range of motion, but affected part(s) are still easily moved 3. Considerable increase in muscle tone, passive movement difficult 4. Affected part(s) rigid in flexion or extension

  up to 6 weeks

• hand grip strength

  hand held dynamometer will be used to assess hand grip strength

  up to 6 weeks

• muscle stiffness

  The MyotonPRO will be used to assess muscle stiffness. it is a new handheld device that conveniently assesses stiffness of muscles and tendons.the device effectively measures changes in muscle stiffness due to fatigue It is placed on the skin over the muscle. A brief, gentle tap from the probe causes the muscle to oscillate. The oscillations are analysed automatically by the device to calculate the muscle's mechanical characteristics, such as its tone, stiffness and how elastic it is.

  up to 6 weeks

Secondary Outcomes (1)

• pain intensity

  up to 6 weeks

Study Arms (2)

low level laser therapy

EXPERIMENTAL

twenty patients will receive low level laser therapy three times a week for 6 weeks

Other: low level laser therapy; Other: selected physical therapy program

selected physical therapy program

ACTIVE COMPARATOR

twenty patients will recieve selected physical therapy program plus sham low level therapy three time a weeks for 6 weeks

Other: selected physical therapy program

Interventions

low level laser therapy OTHER

patients will receive LLT. The LLLT system used in the study (ASA LASER M6) delivered 1.0 W in continuous wave at a wave length in the near infrared of 808 nm. The incident power density will be 670 mW/cm2.The probe head will held with light pressure in contact with the skin over the course of median nerve on the dysfunctional limb for 15 minutes. Protective goggles will be used to prevent direct eye contact of the laser beam. plus selected phyiscal therapy program

low level laser therapy

selected physical therapy program OTHER

patient will receive standard physical therapy program for wrist flexors spasticity post-stroke typically includes the following components: Passive stretching: Passive static or dynamic stretching of the wrist flexorss is the mainstay to reduce spasticity and Physical therapy exercises in form of specific techniques of proprioceptive facilitation, relaxation techniques, passive and self-passive motions, and proper limb positioning. plus sham low level laser therapy

low level laser therapy; selected physical therapy program

Eligibility Criteria

• Age: 45 Years - 60 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• forty stroke patients with wrist flexors spasticity from both sex will be participate in this study
• Their age ranges from 45 to 60 years.
• Patients will be referred by neurological consultants.
• preserved cognitive system, i.e., ability to respond to verbal stimul
• Body mass index less than 30.
• Patients will be diagnosed by clinical and radiological examination.
• patients with wrist flexors spasticity according to modified ashworth scale score +1 to 2.

You may not qualify if:

• Patients with contractures, fractures, rigidity, and deformity
• Patients with cognitive impairments.
• Patients with visual, auditory impairment affecting their ability to complete tasks.
• Uncontrolled Diabetic patient.
• Presence of hypoesthesia and/or hyperesthesia of the involved upper limb.
• Other major neurological condition (e.g., Spinal cord injury, multiple sclerosis, Epilepsy, Meningitis, and Brain tumor).
• presence of neoplastic lesions at the site of application

Sponsors & Collaborators

• Cairo University: lead

MeSH Terms

Conditions

Stroke

Interventions

Low-Level Light Therapy

Condition Hierarchy (Ancestors)

Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases

Intervention Hierarchy (Ancestors)

Laser Therapy; Therapeutics; Phototherapy

Central Study Contacts

heba mohamed, master

CONTACT

01156365322; hebah9355@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Masking Details: opaque sealed envelope
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: principle investigator : heba hassan amin mohamed

Model Details: low level laser therapy and selected phyisical therapy program

Study Record Dates

• First Submitted: September 6, 2025
• First Posted: September 15, 2025
• Study Start: September 15, 2025
• Primary Completion: December 30, 2025
• Study Completion: December 30, 2025
• Last Updated: September 15, 2025

Record last verified: 2025-09