NCT07091708

Brief Summary

Complex regional pain syndrome (CRPS) is a condition marked by pain that may occur spontaneously or in response to stimuli, often disproportionate to the initial injury.(Chae, 2010). In post-stroke complex regional pain syndrome, patients often have simultaneous shoulder and wrist pain. Symptoms may include edema, increased warmth in the hand, and limited in upper extremity joints. (Yu, 2009).The significance of post-stroke complex regional pain syndrome (CRPS) lies not only in its profound impact on pain perception but also in its broader effects on patients' quality of life.(de mos et al.,2007) Managing complex regional pain syndrome involves a multidisciplinary approach with key physical therapy elements like elevation, massage, range of motion exercises, strengthening, and sensory re-education.(Sethy et al., 2017). Electrotherapy modalities include transcutaneous electrical nerve stimulation. (Palmer, 2015). This includes heat treatments like ultrasound, hot and cold packs, and fluidotherapy

Trial Health

65
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
40

participants targeted

Target at P25-P50 for not_applicable stroke

Timeline
1mo left

Started Aug 2025

Shorter than P25 for not_applicable stroke

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress93%
Aug 2025Jun 2026

First Submitted

Initial submission to the registry

July 22, 2025

Completed
7 days until next milestone

First Posted

Study publicly available on registry

July 29, 2025

Completed
17 days until next milestone

Study Start

First participant enrolled

August 15, 2025

Completed
Same day until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 15, 2025

Completed
10 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 15, 2026

Expected
Last Updated

July 29, 2025

Status Verified

July 1, 2025

Enrollment Period

Same day

First QC Date

July 22, 2025

Last Update Submit

July 22, 2025

Conditions

Outcome Measures

Primary Outcomes (1)

  • Visual analogue scale

    Visual analogue scale (VAS) is valuable tool for assessing the intensity and frequency of symptoms, particularly pain.

    5 min

Study Arms (1)

intervention

OTHER
Other: Acupuncture

Interventions

Acupuncture

intervention

Eligibility Criteria

Age45 Years - 60 Years
Sexall(Gender-based eligibility)
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • \. The study involved forty patients male and female aged between 45 and 65 years. 2. A confirmed diagnosis of complex regional pain syndrome through clinical assessment by neurologist using The Budapest criteria for diagnosis of CRPS (Choi et al ., 2013

You may not qualify if:

  • \. Pre-existing history of hand problems and shoulder dysfunction prior to experiencing a stroke . 2. Those with an overactive sympathetic system from alternative causes eg.congestive heart failure,chronic kidney disease(Reynolds \& Minic, 2023) 8 3. individuals with significant musculoskeletal disorders such as rheumatoid arthritis or metabolic disorders including diabetes 4. Pregnancy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Stroke

Interventions

Acupuncture Therapy

Condition Hierarchy (Ancestors)

Cerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesVascular DiseasesCardiovascular Diseases

Intervention Hierarchy (Ancestors)

Complementary TherapiesTherapeutics

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Demonstator

Study Record Dates

First Submitted

July 22, 2025

First Posted

July 29, 2025

Study Start

August 15, 2025

Primary Completion

August 15, 2025

Study Completion (Estimated)

June 15, 2026

Last Updated

July 29, 2025

Record last verified: 2025-07