NCT07166276

Brief Summary

A total of 318 patients applying to Bolu Abant İzzet Baysal University will be included in the study. Based on anamnesis, radiographic examination, and the 2018 classification of periodontal diseases, the participants will be categorized into three groups: periodontal health (n=106), gingivitis (n=106), and periodontitis (n=106). Information regarding participants' coffee consumption habits and their daily coffee intake will be collected. Clinical parameters to be measured will include plaque index, gingival index, bleeding on probing, gingival recession, and clinical attachment level. The frequency of coffee consumption will be evaluated as daily, 1-2 times per week, 3-4 times per week, once per month, twice per month, and once per year. The amount of coffee consumed at a single occasion (cup, glass, mug, etc.) will also be recorded. In caffeinated coffee consumption, the preference for weak, moderate, or strong coffee, as well as consumption with milk, condensed milk, sugar, honey, or sweeteners will be assessed. For Turkish coffee, the consumption pattern will be categorized as unsweetened, moderately sweetened, or sweetened.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
318

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Nov 2024

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 19, 2024

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 28, 2025

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

August 28, 2025

Completed
6 days until next milestone

First Submitted

Initial submission to the registry

September 3, 2025

Completed
7 days until next milestone

First Posted

Study publicly available on registry

September 10, 2025

Completed
Last Updated

November 21, 2025

Status Verified

November 1, 2025

Enrollment Period

8 months

First QC Date

September 3, 2025

Last Update Submit

November 18, 2025

Conditions

Keywords

coffeeperiodontal diseaseperiodontitis

Outcome Measures

Primary Outcomes (3)

  • periodontal pocket depth

    physical methods to measure the distance from the bottom of a pocket to a reference line, usually the gingival margin or the cemento-enamel junction.

    Baseline

  • bleeding on probing

    To test for bleeding after probing, the probe is carefully introduced to the bottom of the pocket and gently moved laterally along the pocket wall. + is maximum and - is minimum.

    baseline

  • Frequency of consumption of fermented foods

    the frequency of fermented foods is measured. The foods questioned were evaluated using a 7-point Likert-type frequency form (every day, 3-4 per week, 1-2 per week, 2 per month, 1 per month, never). In addition, the amounts of foods consumed each time were recorded, and the daily consumption amounts were obtained by dividing them by the frequency of consumption.

    baseline

Secondary Outcomes (3)

  • plaque index

    baseline

  • gingival index

    baseline

  • clinical attachment level

    baseline

Study Arms (3)

Periodontitis

It refers to a chronic inflammatory disease of the supporting tissues of the teeth, characterized by progressive destruction of the periodontal ligament and alveolar bone, with pocket formation and/or gingival recession.

Other: coffee

Gingivitis

It refers to a reversible inflammation of the gingival tissues without loss of periodontal attachment. The condition is primarily induced by dental plaque accumulation and is characterized clinically by signs such as gingival redness, swelling, and bleeding on probing.

Other: coffee

Periodontal health

Periodontal health refers to the absence of clinical signs of inflammation in the periodontium, with stable supporting tissues and no evidence of attachment loss or bone destruction.

Other: coffee

Interventions

coffeeOTHER

The type of coffee consumed, the daily amount of coffee, and the frequency of consumption were measured.

GingivitisPeriodontal healthPeriodontitis

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Individuals with periodontitis, gingivitis, and periodontal disease

You may qualify if:

  • Healthy individuals were between 18 and 65 years

You may not qualify if:

  • Individuals were excluded if they had smoked more than 100 cigarettes in their lifetime, were current smokers, had a diagnosis of uncontrolled diabetes mellitus, were pregnant, or were breastfeeding.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Bolu Abant İzzet Baysal University

Bolu, 14030, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Periodontal DiseasesPeriodontitis

Interventions

Coffee

Condition Hierarchy (Ancestors)

Mouth DiseasesStomatognathic Diseases

Intervention Hierarchy (Ancestors)

Plant PreparationsBiological ProductsComplex MixturesBeveragesDiet, Food, and NutritionPhysiological PhenomenaFood and Beverages

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Assistant professor

Study Record Dates

First Submitted

September 3, 2025

First Posted

September 10, 2025

Study Start

November 19, 2024

Primary Completion

July 28, 2025

Study Completion

August 28, 2025

Last Updated

November 21, 2025

Record last verified: 2025-11

Locations