NCT07164547

Brief Summary

This study aims to investigate the acute effects of Tribulus terrestris supplementation on anaerobic performance and sprint times in trained male combat sport athletes. A total of 28 athletes from kickboxing, Muay Thai, and taekwondo disciplines will participate in a randomized, double-blind, placebo-controlled, crossover trial. Participants will ingest either a single oral dose of 625 mg Tribulus terrestris (40% saponins) or a placebo 60 minutes before performing performance tests. The performance assessments will include a 30-second Wingate anaerobic cycling test and 20 m and 100 m sprint tests using photocell timing gates. After a wash-out period, participants will cross over to the alternate condition. The primary outcomes are peak power and mean power from the Wingate test and sprint times over 20 m and 100 m.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
28

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Mar 2025

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 21, 2025

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 21, 2025

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

August 15, 2025

Completed
16 days until next milestone

First Submitted

Initial submission to the registry

August 31, 2025

Completed
10 days until next milestone

First Posted

Study publicly available on registry

September 10, 2025

Completed
Last Updated

September 10, 2025

Status Verified

September 1, 2025

Enrollment Period

3 months

First QC Date

August 31, 2025

Last Update Submit

September 8, 2025

Conditions

Keywords

Tribulus terrestrisCombat sportsAnaerobic performanceWingate testSprint timeErgogenic supplementation

Outcome Measures

Primary Outcomes (1)

  • Peak Power Output (W, W/kg) - Wingate Test

    Maximum anaerobic power generated during the 30-second Wingate cycling test performed against a resistance equal to 10% of body mass.

    Measured once, 60 minutes after supplementation, during the Wingate test session (single-day assessment).

Secondary Outcomes (1)

  • Mean Power Output (W, W/kg) - Wingate Test

    Measured once, 60 minutes after supplementation, during the Wingate test session (single-day assessment).

Study Arms (2)

Tribulus Terrestris

EXPERIMENTAL

A single oral dose of 625 mg Tribulus terrestris extract (40% saponins) given 60 minutes before exercise testing.

Dietary Supplement: Tribulus terrestris extract

Placebo

PLACEBO COMPARATOR

Visually identical cellulose capsule given 60 minutes before exercise testing.

Other: Cellulose capsule (placebo)

Interventions

Tribulus terrestris extractDIETARY_SUPPLEMENT

625 mg oral capsule (40% saponins), single dose

Tribulus Terrestris

Oral cellulose capsule, identical in appearance

Placebo

Eligibility Criteria

Age18 Years - 30 Years
Sexmale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Male athletes aged 18-30 years
  • Engaged in combat sports (kickboxing, Muay Thai, or taekwondo)
  • Minimum 2 years of continuous training experience
  • Training at least 4 sessions per week
  • Free from injury or illness at the time of testing
  • Provided written informed consent

You may not qualify if:

  • Use of ergogenic supplements, anabolic steroids, or hormonal treatments within the past 3 months
  • Consumption of caffeine, alcohol, or performance-enhancing substances within 24 hours before testing
  • Current musculoskeletal injury or medical condition that may limit performance
  • Any chronic disease or contraindication to high-intensity exercise

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Atatürk University, Sports Science Laboratory

Erzurum, Erzurum, 25240, Turkey (Türkiye)

Location

MeSH Terms

Interventions

Tribulus extractCellulose

Intervention Hierarchy (Ancestors)

GlucansBiopolymersPolymersMacromolecular SubstancesPolysaccharidesCarbohydratesBiomedical and Dental MaterialsManufactured MaterialsTechnology, Industry, and Agriculture

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
QUADRUPLE
Who Masked
PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
Masking Details
Participants, investigators, care providers, and outcome assessors were blinded to group allocation. Supplements were prepared in identical capsules to ensure blinding integrity.
Purpose
TREATMENT
Intervention Model
CROSSOVER
Model Details: This is a randomized, double-blind, placebo-controlled, crossover trial in which all participants received both Tribulus terrestris and placebo supplementation with a wash-out period in between conditions.
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Research Assistant

Study Record Dates

First Submitted

August 31, 2025

First Posted

September 10, 2025

Study Start

March 21, 2025

Primary Completion

June 21, 2025

Study Completion

August 15, 2025

Last Updated

September 10, 2025

Record last verified: 2025-09

Locations