Prefabricated CAD CAM Allogeneic Ring Blocks in the Anterior Maxilla With Immediate Implantation

NCT07163351 | Completed

• 1 other identifier: AUAREC20240001-7
• Study Type: interventional
• Target: 20
• Locations: 1 country
• Sites: 1

Brief Summary

Clinical and radiographic evaluation of a new modification of ring technique using omputeraided design/computer-aided manufacturing (CAD/CAM) milling of allogeneic bone block for anterior maxilla ridge augmentation with immediate implantation

Conditions

Prefabricated; CAD; CAM; Allogeneic Ring Blocks; Anterior Maxilla; Immediate Implantation

Outcome Measures

Primary Outcomes (1)

• Vertical/Horizonal Bone Gain

  Vertical/Horizonal Bone Gain was measured via cone beam computed tomography superimposition at 18 months

  18 months post-procedure

Secondary Outcomes (3)

• Implant Survival Rate

  18 months post-procedure

• Assessment of aesthetic outcome

  18 months post-procedure

• Patient Satisfaction

  18 months post-procedure

Study Arms (1)

Study group

EXPERIMENTAL

Patients presented with anterior maxillary alveolar bone defects resulting from previous implant failure

Other: CAD/CAM allogenic bone block

Interventions

CAD/CAM allogenic bone block OTHER

CAD/CAM allogenic bone block augmentation with immediate non-functional implant loading

Study group

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Aged between 18 and 65 years.
• Both sexes.
• Patients presenting with anterior maxillary alveolar bone defects resulting from previous implant failure.
• Systemically healthy individuals, classified as American Society of Anesthesiologists (ASA) physical status I or II.
• Participants were either non-smokers or light smokers consuming fewer than 10 cigarettes per day.

You may not qualify if:

• Uncontrolled systemic conditions such as diabetes mellitus or osteoporosis.
• Pregnant or breastfeeding at the time of recruitment.
• Individuals with a history of head or neck radiation therapy.
• Cases in which insufficient bone volume for implant placement persisted following augmentation.

Sponsors & Collaborators

• Tanta University: lead

Study Sites (1)

Cairo University

Cairo, 12613, Egypt

Location

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor of Oral Medicine, Periodontology, Oral Diagnosis and Oral Radiology Department, Faculty of Dentistry, Tanta, University, Tanta, Egypt.

Study Record Dates

• First Submitted: August 31, 2025
• First Posted: September 9, 2025
• Study Start: January 1, 2024
• Primary Completion: July 1, 2025
• Study Completion: July 1, 2025
• Last Updated: September 9, 2025

Record last verified: 2025-08

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL
• Time Frame: After the end of study for one year.
• Access Criteria: The data will be available upon a reasonable request from the corresponding author.

Locations

EG (1)