Frequency of Hypermobility-Related Problems in Patients With Anorexia Nervosa

NCT07159867 | Not Yet Recruiting

• 1 other identifier: 2023-00568-01
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to examine the frequense of generalized hypermobility and pain in patients with Anorexia Nervosa. The study further explores two main questions: (1) whether generalized hypermobility may be an explanatory factor for pain in some patients with Anorexia Nervosa, and (2) whether temporomandibular joint problems (such as instability, pain, difficulties opening the mouth, locking, or clicking) contribute to eating difficulties in certain individuals with Anorexia Nervosa.

Conditions

Anorexia Nervosa, Atypical; Anorexia Nervosa

Keywords

Anorexia nervosa; Joint hypermobility; Pain; Temporomandibular joint

Outcome Measures

Primary Outcomes (2)

• Joint hypermobility

  Joint mobility will be assessed according to the Beighton score using a goniometer.

  One-time assessment at baseline (Day 0, at the inclusion visit).

• 5-part questionnaire

  Participants over the age of 18 will also complete the 5-part questionnaire regarding historical hypermobility.

  One-time questionnaire at baseline (Day 0, after clinical examination).

Secondary Outcomes (3)

• Joint pain

  One-time questionnaire at baseline (Day 0, after clinical examination).

• Temporomandibular joint problems

  One-time questionnaire at baseline (Day 0, after clinical examination).

• Pain drawing

  One-time questionnaire at baseline (Day 0, after clinical examination).

Study Arms (1)

Female patients diagnosed with Anorexia Nervosa or Atypical Anorexia Nervosa, aged 13-25 years.

Eligibility Criteria

• Age: 13 Years - 25 Years
• Sex: female
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Patients at the Eating Disorders Center for Children and Young Adults in Gothenburg.

You may qualify if:

• Female patients Aged 13-25 years
• Diagnosed with:
• Anorexia Nervosa (ICD-10 F50.0), or
• Atypical Anorexia Nervosa (ICD-10 F50.1)
• Currently receiving treatment or scheduled to receive treatment

You may not qualify if:

• Severe cognitive impairment
• Insufficient Swedish language skills that make it impossible to provide informed consent and prevent answering study questions
• Pregnancy and up to one year postpartum

Sponsors & Collaborators

• Vastra Gotaland Region: lead

Study Sites (1)

Queen Silvias Children´s Hospital

Gothenburg, Västra Götaland County, 416 50, Sweden

Location

MeSH Terms

Conditions

Anorexia Nervosa; Joint Instability; Pain

Condition Hierarchy (Ancestors)

Feeding and Eating Disorders; Mental Disorders; Joint Diseases; Musculoskeletal Diseases; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Central Study Contacts

Elke Schubert Hjalmarsson, PhD

CONTACT

+46700824535; elke.schubert@vgregion.se

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Dr

Study Record Dates

• First Submitted: August 21, 2025
• First Posted: September 8, 2025
• Study Start: September 15, 2025
• Primary Completion (Estimated): July 30, 2026
• Study Completion (Estimated): July 30, 2026
• Last Updated: September 8, 2025

Record last verified: 2025-08

Data Sharing

• IPD Sharing: Will not share

Locations

SE (1)