An Open Label 100 Person Study Evaluating a Natural Supplement for Weight Loss and Fat Loss.

NCT07152470 | Active Not Recruiting

• 1 other identifier: Motus1001
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this clinical trial is to learn if motus, a natural supplement can support healthy weight loss and fat loss in a real world setting without caloric restrictions or exercise requirements. The main questions it aims to answer are: Can a daily dose of motus result in statistically significant weight loss over 3 month and 6 month time points. Participants will: Weigh-in at baseline and every week thereafter Take drug motus every day Complete a food tracker app for every meal and drink product consumed daily Complete an exercise tracker for any activities performed daily Complete weekly satisfaction surveys on various topics

Conditions

Overweight and Obesity

Outcome Measures

Primary Outcomes (2)

• Total Weight Loss

  Total weight loss as a percentage of total body weight

  26 weeks

• Body Fat Loss

  Total body fat loss compared to lean mass loss

  26 weeks

Study Arms (4)

Healthy Diet with Daily Exercise (>4 days per week)

Participants consumed a strict healthy diet and daily exercise (\>30 mins) as determined by nutritionists who were randomly assigned to participants to review their wellness tracker and conduct periodic 1:1 coaching sessions

Behavioral: Diet and Exercise Tracking

Average Diet with Moderate Exercise (2-3 days per week)

Participants consumed an average diet with 2-3 days of exercise per week (\>30 mins) as determined by nutritionists who were randomly assigned to participants to review their wellness tracker and conduct periodic 1:1 coaching sessions

Behavioral: Diet and Exercise Tracking

Average Diet with No Exercise (0 days per week)

Participants consumed an average diet with zero days of exercise per week as determined by nutritionists who were randomly assigned to participants to review their wellness tracker and conduct periodic 1:1 coaching sessions

Behavioral: Diet and Exercise Tracking

Poor Diet with No Exercise (0 days per week)

Participants consumed a poor diet with zero days of exercise per week as determined by nutritionists who were randomly assigned to participants to review their wellness tracker and conduct periodic 1:1 coaching sessions

Behavioral: Diet and Exercise Tracking

Interventions

Diet and Exercise Tracking BEHAVIORAL

To determine if diet and/or exercise had any impact on weight loss while taking motus.

Average Diet with Moderate Exercise (2-3 days per week); Average Diet with No Exercise (0 days per week); Healthy Diet with Daily Exercise (>4 days per week); Poor Diet with No Exercise (0 days per week)

Eligibility Criteria

• Age: 18 Years - 75 Years
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

100 patients in the United states

You may qualify if:

• BMI \>25
• Willing to complete daily diary and weekly weigh-ins
• Willing to take motus daily

You may not qualify if:

• BMI\<25
• Unwilling to complete daily diary and weekly weigh-ins
• Currently taking a prescribed weight loss medication
• Currently or planning to be pregnant

Sponsors & Collaborators

• Prostasis, LLC, dba Tonum Health: lead

Study Sites (1)

Tonum Health

West Palm Beach, Florida, 33401, United States

Location

MeSH Terms

Conditions

Overweight; Obesity

Interventions

Diet

Condition Hierarchy (Ancestors)

Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Nutritional Physiological Phenomena; Diet, Food, and Nutrition; Physiological Phenomena

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: INDUSTRY
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 26, 2025
• First Posted: September 3, 2025
• Study Start: January 26, 2025
• Primary Completion: July 26, 2025
• Study Completion: December 26, 2025
• Last Updated: September 9, 2025

Record last verified: 2025-09

Locations

US (1)