A Comparison Between Biportal and Uniportal Endoscopic Lumbar Discectomy

NCT07151651 | Not Yet Recruiting DMC

• 1 other identifier: Sohag-Med-25-8---4MD
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to provide a detailed comparison between different methods of lumbar discectomy by the use of different types of spine endoscopy to evaluate the benefits and drawbacks of each type

Conditions

Lumbar Disc Herniation

Keywords

Lumar discectomy; Endoscopy; Uniportal; Biportal

Outcome Measures

Primary Outcomes (1)

• Primary outcome measures After endoscopic lumbar discectomy Pain relief

  1-Pain Relief: Visual Analog Scale (VAS for leg and back pain)

  12 weeks up to 2 years

Study Arms (1)

Patients with lumbar disc prolapse

ACTIVE COMPARATOR

1. Patients aged 18-70 years. 2. single-level lumbar disc herniation (L3-L4, L4-L5, or L5-S1) confirmed by MRI. 3. Persistent symptoms not responding to conservative management (≥6 weeks).

Procedure: Endoscopic lumbar discectomy

Interventions

Endoscopic lumbar discectomy PROCEDURE

Uniportal and boportal endoscopic lumbar discectomy (transforaminal or interlaminar)

Patients with lumbar disc prolapse

Eligibility Criteria

• Age: 18 Years - 70 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• All patients should fulfill the following criteria
• Patients aged 18-70 years.
• single-level lumbar disc herniation (L3-L4, L4-L5, or L5-S1) confirmed by MRI.
• Persistent symptoms not responding to conservative management (≥6 weeks).

You may not qualify if:

• All patients should not have any of the following criteria
• Multilevel disc herniation.
• Previous lumbar spine surgery, trauma or injection.
• Severe spinal stenosis.
• Severe osteoporosis, infection, or malignancy or autoimmune disease affecting the spine.
• Uncontrolled medical comorbidities contraindicating surgery.
• Instability: spondylolisthesis\>grade 1
• Marked obesity.(BMI \>35-40 kg/m2 )

Sponsors & Collaborators

• Sohag University: lead

Study Sites (1)

Sohag University

Sohag, Sohag Governorate, 002, Egypt

Location

MeSH Terms

Conditions

Intervertebral Disc Displacement

Condition Hierarchy (Ancestors)

Spinal Diseases; Bone Diseases; Musculoskeletal Diseases; Hernia; Pathological Conditions, Anatomical; Pathological Conditions, Signs and Symptoms

Central Study Contacts

mohamed Ibrahim Amin, Assesstant lecturer

CONTACT

002 010 215 64439; Mohamed-ataya@med.sohag.edu.eg

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant lecturer at neurosurgery department sohag University

Model Details: A prospective study will be conducted at Sohag and Cairo University Hospitals on 60 patients diagnosed with lumbar disc herniation, undergoing endoscopic lumbar discectomy.

Study Record Dates

• First Submitted: August 19, 2025
• First Posted: September 3, 2025
• Study Start: September 1, 2025
• Primary Completion (Estimated): September 1, 2026
• Study Completion (Estimated): September 1, 2027
• Last Updated: September 3, 2025

Record last verified: 2025-08

Locations

EG (1)