Multi-modal Intelligent Diagnosis System for Multiple Ophthalmic Diseases

NCT07143851 | Not Yet Recruiting

• 1 other identifier: BJ-2025-092
• Study Type: observational
• Target: 5,000
• Locations: 0 countries
• Sites: N/A

Brief Summary

Aiming at the problems of low image reading efficiency, crowded medical resources and fragmented cross-modal information of ophthalmic OCT and OCTA, a multimodal large model diagnostic framework for various diseases such as retinal diseases and optic nerve damage in glaucoma is constructed to fully explore the complementary information of various images such as SS-OCT structural images, SS-OCTA vascular images and optic nerve scans. Extract cross-modal joint features to improve the accuracy of automatic diagnosis.

Conditions

Retina Disease; Glaucoma

Outcome Measures

Primary Outcomes (1)

• CMT

  Central macular thickness measured on OCT

  Baseline

Secondary Outcomes (1)

• SS-OCT/OCTA images

  Baseline

Interventions

Not applicable- observational study OTHER

There is no special intervention method

Eligibility Criteria

• Age: 20 Years - 90 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Patients diagnosed as macular degeneration, diabetic macular edema, retinal vein obstructive macular edema, high myopia, glaucoma or other clearly diagnosed ophthalmic diseases.

You may qualify if:

• Diagnosed as macular degeneration, diabetic macular edema, retinal vein obstructive macular edema, high myopia, glaucoma or other clearly diagnosed ophthalmic diseases. The SS-OCT/SS-OCTA images of the patient are clear.

You may not qualify if:

• The image quality is poor and difficult to analyze due to reasons such as refractive media opacity and poor coordination.

Sponsors & Collaborators

• Beijing Hospital: lead

MeSH Terms

Conditions

Glaucoma

Condition Hierarchy (Ancestors)

Ocular Hypertension; Eye Diseases

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Target Duration: 1 Day
• Sponsor Type: OTHER GOV
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 29, 2025
• First Posted: August 27, 2025
• Study Start: August 30, 2025
• Primary Completion (Estimated): June 30, 2028
• Study Completion (Estimated): June 30, 2028
• Last Updated: August 27, 2025

Record last verified: 2025-08

Data Sharing

• IPD Sharing: Will not share