NCT07141342

Brief Summary

This project will complete the final design and development steps to commercialize the Fast In-Bed Tracking (FIT) Platform, which is an e-Health and wellness Internet of Things (IoT) monitoring system that can be integrated into a user's bed and provide person-centered, real-world outcomes to support health and wellness. The technical feasibility of FIT was proven over the past several years and has demonstrated the platform can support the treatment of several chronic conditions across different populations, including obesity, congestive heart failure, and pressure injuries. The project goals will be to (1) complete design refinements for FIT and (2) demonstrate the platform's efficacy to support weight loss goals of wheelchair users. Wheelchair users are twice as likely as the general population to be overweight or obese and excess weight not only exacerbates mobility and participation limitations but increases risk for secondary health problems. Evidence reveals that frequent weight monitoring is a key driver for weight management, which puts wheelchair users at a significant disadvantage, because they have no convenient way to measure their body weight. As a recent example, lack of participant's ability to self-weigh was a noted limitation to a weight loss program for wheelchair users, known as the Group Lifestyle Balance weight loss program Adapted for Individuals with Impaired Mobility (GLB-AIM). FIT solves this challenge by passively monitoring a user's weight when they get on and off their bed. The investigators lab and community-based feasibility trials demonstrated that FIT successfully tracks weight for individuals and couples sharing a bed and that users find FIT highly usable. This proposed project will allow the investigators to complete the design refinements participants recommended during our community-based feasibility trial and subsequently examine the efficacy of FIT in supporting the weight-loss goals of community-dwelling wheelchair users through a randomized controlled trial using the GLB-AIM.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
92

participants targeted

Target at P50-P75 for not_applicable

Timeline
16mo left

Started Feb 2026

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress14%
Feb 2026Sep 2027

First Submitted

Initial submission to the registry

August 13, 2025

Completed
13 days until next milestone

First Posted

Study publicly available on registry

August 26, 2025

Completed
6 months until next milestone

Study Start

First participant enrolled

February 16, 2026

Completed
1.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2027

Expected
5 months until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2027

Last Updated

February 23, 2026

Status Verified

February 1, 2026

Enrollment Period

1.1 years

First QC Date

August 13, 2025

Last Update Submit

February 20, 2026

Conditions

Keywords

WheelchairWheelchair UsersWeigh lossWeight loss deviceWeight loss programdevice researchbed scaleWheelchair Scale

Outcome Measures

Primary Outcomes (1)

  • Weight Loss after 6 and 12 months comparing the intervention group (FIT bed scale with daily weight feedback) versus control group (weighed at baseline, 6 and 12 months)

    The difference in weight loss from baseline to 6 and 12 months (intervention versus control groups).

    Baseline, Month 6, Month 12

Secondary Outcomes (8)

  • Participant's Adherence to the Diet and Exercise Intervention (Average Days Per Week of Food Tracking)

    Baseline to Month 12

  • Participant's Average Daily Caloric Intake when Tracking Food

    Baseline to Month 12

  • Changes in Participant's Body Composition

    Baseline, Month 6, Month 12

  • Changes in Participant's Dietary Intake

    Baseline, 6 and 12 months

  • Average weekly minutes of physical activity (strength, aerobic)

    Baseline to Month 12

  • +3 more secondary outcomes

Study Arms (2)

GLB-AIM

ACTIVE COMPARATOR

All participants in the control group will receive the Group Lifestyle Balance Adapted for Individuals with Impaired Mobility (GLB-AIM) intervention. The investigators anticipate a total of 46 participants will be randomized to the control group. THE GLB-AIM is a 12-month intervention with a total of 23 sessions: 13 weekly core sessions to start the program, followed by 3 bi-weekly support sessions, and reducing to 1 monthly support session for the final 7 months. Control participants will be asked to download the My Net Diary app onto their personal phone and to log daily food intake and exercise using the app for the first 13 weeks of the GLB-AIM program. All subjects in the study will be enrolled in the GLB-AIM intervention; the only difference between the experimental and control group is that the control group will not receive the Fast In Bed Tracking System (FIT) scale during the study and therefore will not have the ability to self-monitor their weight.

Behavioral: Group Lifestyle Balance Adapted for Individuals with Impaired Mobility (GLB-AIM) intervention

GLB-AIM + FIT Weight Scales

EXPERIMENTAL

All participants in the experimental group will receive the Group Lifestyle Balance Adapted for Individuals with Impaired Mobility (GLB-AIM) intervention and will be asked to download the My Net Diary app. The investigators anticipate a total of 46 participants will be randomized to the experimental group. Participants who are randomized to the FIT Weight Scale Group will have the FIT scale set up in-home during the baseline visit by research team members. Intervention participants will be oriented to their scale if randomized into the FIT scale group. Participants will be asked to enter their weight daily into the My Net Diary app.

Device: The Fast In-Bed Tracking System (FIT) Weight ScaleBehavioral: Group Lifestyle Balance Adapted for Individuals with Impaired Mobility (GLB-AIM) intervention

Interventions

It is hypothesized that wheelchair users who are randomized into the FIT Weight Scales group will lose a significantly greater percent of body weight over time (6 months, 12 months) than wheelchair users randomized to the control group.

GLB-AIM + FIT Weight Scales

The GLB-AIM is a direct adaptation of the Diabetes Prevention Program (DPP) - Group Lifestyle Balance (DPP-GLB) which has successfully yielded an average 6 percent weight loss at 12 months and reduced diabetes risk over 2.8 years by 58 percent, which was 39 percent lower than participants randomized to the metformin group. The GLB-AIM which has been proven feasible and effective in a pilot study and a randomized control trial (RCT) with 67 mobility impaired individuals randomized to the intervention group or a waitlist control group. There were significant between group differences in weight loss at 6 months (-1.7 kg loss vs 0.05 kg gain, p \<0.05) and combined results from both groups after receiving the intervention revealed an average weight loss at 12 months of 3.3 percent of their starting weight. Notably, the average loss was lower than the 5 to 7 percent achieved by diverse participants in the DPP-GLB trials.

GLB-AIMGLB-AIM + FIT Weight Scales

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age18 +
  • Live within approximately 75 miles of Pittsburgh
  • Uses a wheelchair as primary means of locomotion
  • Currently transfers in and out of bed every night (or most nights)
  • Has been diagnosed as obese or overweight
  • Are interested in losing weight
  • BMI in the range of approximately 25 to 40; BMI range will be determined from published evidence for the primary diagnosis of the participant. For example, spinal cord injury /quadriplegic BMI range of approximately 22 to 40; for amputees it will be based on location and level of amputation, or if no diagnosis specific evidence exists, a BMI of approximately 25 to 40 will be used as a general guideline.
  • Own a smart phone, and have reliable internet and wifi connection
  • Are comfortable using exercise equipment like resistance bands or hand pedal exercisers
  • Are able and willing to engage in exercise of moderate intensity
  • Weight in bed including sleep partner is an estimated combined weight of 600 pounds or less
  • Does not have a regular way to weigh themselves, such as a roll-on scale in the home or gym, or have regular access to a device to weigh themselves regularly and are willing to avoid weighing themselves during the trial.
  • Indication that the participant has autonomy in decision-making as determined by the "Everyday Autonomy Self-Determination Scale."
  • Indication that their current bedroom setup is compatible with the FIT bed scales as determined by the "Bed Determination Survey."

You may not qualify if:

  • Extended vacations or absences planned in the next year (more that 2 - 4 weeks) or plans to move approximately 75 miles or greater from the Pittsburgh region
  • BMI outside of the desired range as based on condition and as determined by the study team.
  • Currently taking weight loss medication, medications that affect appetite, or have had weight loss surgery in the last 2 years.
  • History disordered eating in the last 2 years, such as Anorexia Nervosa, Bulimia Nervosa or Binge Eating Disorder
  • Currently pregnant or intend to become pregnant in the next 12 months
  • Regularly have 4 or more alcoholic drinks a day
  • Have any cognitive conditions that limit decision making or self-governing.
  • Indication that the participant does not have autonomy in decision-making as determined by the "Everyday Autonomy Self-Determination Scale."
  • Indication that their current bedroom setup is not compatible with the FIT bed scales as determined by the "Bed Determination Survey."

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Pittsburgh, Bakery Square, Department of Rehabilitation Science and Technology

Pittsburgh, Pennsylvania, 15206, United States

RECRUITING

Related Links

MeSH Terms

Conditions

ObesityOverweight

Interventions

Methods

Condition Hierarchy (Ancestors)

OvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Investigative Techniques

Study Officials

  • Jonathan Pearlman, PhD

    University of Pittsburgh

    PRINCIPAL INVESTIGATOR
  • Katherine Froehlich-Grobe, PhD

    Craig Hospital

    STUDY DIRECTOR

Central Study Contacts

Daniel Rusnak, MS

CONTACT

Jonathan Pearlman, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
OTHER
Intervention Model
PARALLEL
Model Details: Randomized control trial
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

August 13, 2025

First Posted

August 26, 2025

Study Start

February 16, 2026

Primary Completion (Estimated)

April 1, 2027

Study Completion (Estimated)

September 1, 2027

Last Updated

February 23, 2026

Record last verified: 2026-02

Data Sharing

IPD Sharing
Will not share

IPD will not be shared as a condition of IRB approval and individual experiences of the clinical trial will not be of clinical relevance to the field. Aggregate data will be released as to the efficacy of the device to be studied in the clinical trial.

Locations