NCT07225426

Brief Summary

The purpose of this study is to determine the feasibility of providing personalized incentives for dietary self-monitoring and/or interim weight loss to people enrolled in a weight-loss program

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
80

participants targeted

Target at P50-P75 for not_applicable

Timeline
10mo left

Started Feb 2026

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress24%
Feb 2026Feb 2027

First Submitted

Initial submission to the registry

November 4, 2025

Completed
2 days until next milestone

First Posted

Study publicly available on registry

November 6, 2025

Completed
3 months until next milestone

Study Start

First participant enrolled

February 4, 2026

Completed
1.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 28, 2027

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 28, 2027

Last Updated

March 6, 2026

Status Verified

March 1, 2026

Enrollment Period

1.1 years

First QC Date

November 4, 2025

Last Update Submit

March 5, 2026

Conditions

Keywords

behavioral interventionobesityfinancial incentivesreinforcement learningartificial intelligence

Outcome Measures

Primary Outcomes (2)

  • Screening-to-enrollment ratio

    number of potential participants screened for the study/ number of participants who provide a baseline weight for the intervention

    Week 0

  • Retention for outcomes

    number of participants who provide a weight at 25 weeks/number of participants who provide a baseline weight for the intervention

    25 weeks

Secondary Outcomes (3)

  • Adherence to calorie logging

    24 weeks

  • Adherence to self-weighing

    24 weeks

  • Body weight

    baseline to 25 weeks

Study Arms (1)

Personalized incentives

EXPERIMENTAL

Participants may receive financial incentives for weight loss if their performance suggests they respond to financial incentives.

Behavioral: personalized financial incentives

Interventions

Every week, a reinforcement learning algorithm will process data on weight loss, calorie logging, and incentives earned to predict that their weight loss is positively influenced by incentives.

Personalized incentives

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Willing to attend virtual baseline and follow-up data collection visits
  • At least 18 years of age
  • Verified obesity as defined as a BMI ≥30 kg/m2
  • Agree to attend 13 biweekly group classes (virtual) delivered by a registered dietitian
  • Agree to review study materials between classes
  • Regular access to an unshared smart phone
  • Reliable access to internet
  • Able to speak and read English
  • Desire to lose weight
  • Able to connect to a video conference call using a smartphone, tablet or computer with a webcam and microphone
  • Ability to download and use Fitbit app daily
  • Have or be willing to create a Gmail address
  • Physical ability to stand on a scale without support

You may not qualify if:

  • Weight loss of at least 10lbs in the month prior to screening
  • Weight \> 380lbs
  • Currently enrolled or enrolled in the previous month in a clinical, research, or community program focusing on lifestyle change that could affect weight
  • New user of weight loss medication
  • Pregnant, lactating or planning on becoming pregnant during the study
  • History of bariatric procedure or planning to have bariatric procedure in the study timeframe
  • Residing in a nursing home, skilled nursing facility or assisted living facility
  • Impaired hearing
  • Significant dementia, drug or alcohol abuse, or unstable psychiatric illness (e.g., schizophrenia, psychosis)
  • Current treatment for cancer or being treated for cancer (besides basal cell carcinoma or squamous cell) in the last 6 months
  • Use of insulin, sulfonylureas, or meglitinides due to increased risk for hypoglycemia
  • Diuretic medication doses higher than hydrochlorothiazide or chlorthalidone 25 mg daily, furosemide 40 mg daily, torsemide 20 mg daily, bumetanide 1 mg daily, or any use of metolazone; use of potassium-sparing diuretics is acceptable
  • Unstable heart disease in the 6 months prior to screening
  • Chronic kidney disease at stage 4 or higher
  • Exertional chest pain
  • +4 more criteria

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Utah

Salt Lake City, Utah, 84108, United States

RECRUITING

MeSH Terms

Conditions

ObesityOverweight

Condition Hierarchy (Ancestors)

OvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and Symptoms

Central Study Contacts

Fiona Robertson

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

November 4, 2025

First Posted

November 6, 2025

Study Start

February 4, 2026

Primary Completion (Estimated)

February 28, 2027

Study Completion (Estimated)

February 28, 2027

Last Updated

March 6, 2026

Record last verified: 2026-03

Data Sharing

IPD Sharing
Will share

This study will collect weight data from the cellular-connect scales, calorie logging data from the dietary tracking app, and self-reported survey data including demographics and behavioral measures. Additional data will include binary indicators for whether participants earned an incentive each week of the study and how much they earned, generated by algorithms created by the research team using scale and dietary tracking app data.

Shared Documents
STUDY PROTOCOL, SAP, ICF
Time Frame
Scientific data will be available by the earlier of these two time points, as required by the NIH: 1) the date on which the article is first made available in print or electronic format, or 2) the funding period (to include a possible no-cost extension).

Locations