Using ChatGPT to Help Guide Treatment for Sinus and Nasal Problems

NCT07140250 | Completed

• 1 other identifier: 810119
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this clinical trial is to evaluate whether ChatGPT can improve shared decision-making by increasing treatment-related knowledge and reducing decisional conflict in adult patients with chronic rhinosinusitis (CRS) or nasal obstruction who have been deemed candidates for surgery. The main questions it aims to answer are:

• Does ChatGPT improve patient understanding of CRS/nasal obstruction treatment options compared to widely utilized web searches?
• Does ChatGPT reduce decisional conflict regarding surgical versus medical management compared to traditional search engine? Researchers will compare a group using Google (standard internet search with AI turned off) after standard counseling to a group using ChatGPT after standard counseling to see if ChatGPT leads to higher knowledge scores, lower decisional conflict scores, and higher satisfaction with the information platform. Participants will:
• Complete baseline surveys assessing demographics, treatment-related knowledge, and decisional conflict
• Be randomized to use either Google or ChatGPT to research their surgery for 10 minutes after standard in-office counseling
• Complete follow-up surveys assessing knowledge, decisional conflict, and satisfaction with the information source
• Allow the research team to review their medical record for relevant clinical history and disease-specific quality-of-life scores (SNOT-22)

Conditions

Sinusitis; Nasal Obstruction; Rhinitis

Keywords

sinusitis; shared decision making; rhinitis; chatGPT; nasal obstruction

Outcome Measures

Primary Outcomes (1)

• Decisional Conflict Scale (DCS) score

  Change in Decisional Conflict Scale (DCS) score

  Immediate - Following completion of education using AI vs traditional education

Secondary Outcomes (2)

• System usability scale (SUS) scores

  Immediate following education

• Score on treatment-related knowledge questionnaire (MCQ)

  Immediate following education

Study Arms (2)

Shared Decision Making on Sinusitis Treatment Facilitated by ChatGPT

ACTIVE COMPARATOR

Shared decision making (SDM) about sinusitis treatment will be facilitated by ChatGPT through participant driven question and answers using AI support via ChatGPT

Other: Education with AI Technology

Shared Decision Making on Sinusitis Treatment Facilitated by Google

PLACEBO COMPARATOR

Shared decision making (SDM) about sinusitis treatment will be facilitated by traditional internet search engines (Google) with AI mode off. Participate education on sinusitis treatment will be driven by traditional internet searches

Other: Education using Traditional Internet Search Engines

Interventions

Education with AI Technology OTHER

Shared decision making (SDM) about sinusitis treatment will be facilitated by AI technology via ChatGPT

Shared Decision Making on Sinusitis Treatment Facilitated by ChatGPT

Education using Traditional Internet Search Engines OTHER

Participant Education in Sinusitis using Traditional Internet Search Engines through Google

Shared Decision Making on Sinusitis Treatment Facilitated by Google

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Adult (18 years or older) UC San Diego Health System Rhinology patients
• Diagnosis of chronic rhinosinusitis and/or nasal obstruction based on clinical criteria or radiologic evidence
• Planning to pursue surgical intervention for CRS or nasal obstruction
• Ability to complete online survey in English or Spanish

You may not qualify if:

• Unable to complete survey assessments online via REDCap
• Under the age of 18 years
• Vulnerable patient populations such as those who are pregnant and institutionalized individuals
• Patients with benign and malignant tumors

Sponsors & Collaborators

• Carol Yan: lead

Study Sites (1)

UC San Diego

La Jolla, California, 92037, United States

Location

MeSH Terms

Conditions

Sinusitis; Nasal Obstruction; Rhinitis

Interventions

Educational Status

Condition Hierarchy (Ancestors)

Respiratory Tract Infections; Infections; Paranasal Sinus Diseases; Nose Diseases; Respiratory Tract Diseases; Otorhinolaryngologic Diseases; Airway Obstruction; Respiratory Insufficiency; Respiration Disorders

Intervention Hierarchy (Ancestors)

Socioeconomic Factors; Population Characteristics

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: HEALTH SERVICES RESEARCH
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Associate Professor of Otolaryngology

Study Record Dates

• First Submitted: August 18, 2025
• First Posted: August 24, 2025
• Study Start: June 1, 2024
• Primary Completion: January 1, 2025
• Study Completion: January 1, 2025
• Last Updated: August 24, 2025

Record last verified: 2025-08

Locations

US (1)