The Effect of Nasal Hair on Nasal Obstruction
The Effect of Vibrissae on Subjective and Objective Measures of Nasal Obstruction
1 other identifier
interventional
60
1 country
1
Brief Summary
Nasal obstruction is a common complaint prompting presentation to an otolaryngologist. Many studies have been performed quantifying and describing the impact of a number of factors on symptoms of nasal obstruction, including anatomical, neoplastic, infectious, and inflammatory causes. Despite this scrutiny, no attention has been paid to the nasal vibrissae as a potential anatomical contributor to nasal obstruction. The proposed study intends to elucidate that contribution, if any exists.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started May 2013
Shorter than P25 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
May 1, 2013
CompletedFirst Submitted
Initial submission to the registry
May 3, 2013
CompletedFirst Posted
Study publicly available on registry
May 9, 2013
CompletedPrimary Completion
Last participant's last visit for primary outcome
October 1, 2013
CompletedStudy Completion
Last participant's last visit for all outcomes
October 1, 2013
CompletedApril 22, 2019
April 1, 2019
5 months
May 3, 2013
April 19, 2019
Conditions
Keywords
Outcome Measures
Primary Outcomes (2)
Nasal airflow/pressure
Objective measures include airflow and pressure as assessed by Rhinomanometry.
Participants will undergo assessment over a 30 minute period, no follow-up
Subjective Nasal Obstruction
Subjective measures will be assessed via the modified version of the NOSE outcome instrument-a validated test of subjective nasal obstruction
Participants will undergo assessment over a 30 minute period, no follow-up
Study Arms (1)
Vibrissae trimming
EXPERIMENTALPatients will serve as their own control, with assessment of primary outcomes pre- and post-trimming of vibrissae.
Interventions
Patients will have oxymetazoline administered prior to assessment of outcome measures to ensure minimal impact of erectile mucosal tissue on measurement.
Afrin will be administered to minimize the impact of erectile mucosal tissue on obstruction.
Eligibility Criteria
You may qualify if:
- Presence of nasal vibrissae
- Able to tolerate rhinomanometry
You may not qualify if:
- Anatomical or other obvious cause of obstruction
- Claustrophobia with rhinomanometry mask
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Mayo Cliniclead
Study Sites (1)
Mayo Clinic in Rochester
Rochester, Minnesota, 55905, United States
Related Publications (1)
Ozturk AB, Damadoglu E, Karakaya G, Kalyoncu AF. Does nasal hair (vibrissae) density affect the risk of developing asthma in patients with seasonal rhinitis? Int Arch Allergy Immunol. 2011;156(1):75-80. doi: 10.1159/000321912. Epub 2011 Mar 30.
PMID: 21447962BACKGROUND
Related Links
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Grant Hamilton, MD
Mayo Clinic
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NA
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Principal Investigator
Study Record Dates
First Submitted
May 3, 2013
First Posted
May 9, 2013
Study Start
May 1, 2013
Primary Completion
October 1, 2013
Study Completion
October 1, 2013
Last Updated
April 22, 2019
Record last verified: 2019-04