Pleural Tissue Culture Versus Pleural Fluid Culture in Infected Effusion

NCT07140003 | Enrolling By Invitation DMC

• 1 other identifier: pleura,tissue culture,sonograp
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

comparison between the result of fluid culture and that of pleural tissue culture

Conditions

Pleural Tissue Culture

Keywords

pleural tissue culture ,infected pleural fluid

Outcome Measures

Primary Outcomes (2)

• initial pleural fluid and parietal pleural tissue

  the result of culture

  2 weeks

• result of culture

  the result of pleural fluid culture and the pleural tissue culture result

  one month

Study Arms (2)

one group of patients will undergo pleural fluid culture taken by ultrasound chest by 18 gauge needl

ACTIVE COMPARATOR

microbiological culture of the fluid

Procedure: pleural biopsy

sonographic guided pleural tissue culture

ACTIVE COMPARATOR

pareital pleural biobsy will be taken from the posterior costal pleura by ultrasound via true cut biopsy 12 french and tissue will be sent to the micro alab

Procedure: pleural biopsy

Interventions

pleural biopsy PROCEDURE

To assess whether pleural tissue culture can improve the identification of causative organisms in pleural infections (using the pleural fluid culture), which can aid in selecting appropriate antimicrobial therapy and improve treatment outcomes, thus may provide valuable insights into the utility of pleural tissue culture in managing pleural infection and may guide clinicians in selecting the most appropriate diagnostic approach.

one group of patients will undergo pleural fluid culture taken by ultrasound chest by 18 gauge needl; sonographic guided pleural tissue culture

Eligibility Criteria

• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

Sponsors & Collaborators

• Alexandria University: lead

Study Sites (1)

Chest Department -Faculty of Medicine

Alexandria, Chest Department, 11511, Egypt

Location

Related Links

• national library of information

Study Officials

• mohamed sabry eltarhony, lecturer

  Alexandria University

  PRINCIPAL INVESTIGATOR

• hatem essam hamed, lecturer

  Alexandria University

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: DIAGNOSTIC
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: MICROBIOLOGICAL VALUE OF SONOGRAPHIC GUIDED PLEURAL TISSUE CULTURE PLUS PLEURAL FLUID CULTURE IN PATIENTS WITH INFECTED PLEURAL FLUID

Study Record Dates

• First Submitted: August 12, 2025
• First Posted: August 24, 2025
• Study Start: July 1, 2025
• Primary Completion: September 1, 2025
• Study Completion: October 1, 2025
• Last Updated: August 24, 2025

Record last verified: 2025-07

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)