Effect of the Aspiration Care Bundle on Preventing VAP

NCT07138651 | Not Yet Recruiting

• 1 other identifier: 2025/415
• Study Type: interventional
• Target: 60
• Locations: 0 countries
• Sites: N/A

Brief Summary

Many pharmacological and non-pharmacological interventions are used to prevent ventilator-associated pneumonia (VAP). Nurses are directly responsible for implementing non-pharmacological interventions and therefore have an important role in preventing VAP. The most important non-pharmacological nursing interventions to prevent VAP are hand hygiene and oral care. In addition, the head of the bed should be elevated to 30°-45°, head pressure should be monitored, and subglottic aspiration should be performed. Various care packages have been developed to prevent VAP. It has been determined that these care packages reduce the incidence of VAP. The aim of this study was to investigate the effect of the aspiration care package applied in the intensive care unit on preventing the development of ventilator-associated pneumonia, and it was planned as a quasi-experimental study.

Conditions

VAP - Ventilator Associated Pneumonia; Care; Bundle Care; Aspiration; Nursing Care

Outcome Measures

Primary Outcomes (2)

• Clinical Pulmonary Infection Score

  Clinical Pulmonary Infection Score (CPIS): The CPIS is a clinical scoring system developed to facilitate the diagnosis of ventilator-associated pneumonia (VAP). It combines clinical, radiological, physiological, and microbiological parameters to provide a structured assessment of pulmonary infection in critically ill patients. Parameters evaluated in CPIS: * Temperature (fever or hypothermia) * Leukocyte count (leukocytosis, leukopenia, or normal range) * Tracheal secretions (absence, non-purulent, or purulent) * Arterial oxygenation (PaO₂/FiO₂ ratio) * Chest radiograph findings (infiltrates: absent, diffuse, or localized) * Culture of tracheal aspirate (no growth, light, or heavy growth of pathogenic bacteria) A total score \>6 is commonly considered suggestive of pneumonia.

  Through study completion, an average of 35 days

• VAP rate monitoring form

  Through study completion, an average of 35 days

Study Arms (1)

Conrol group

OTHER

Rutin aspiration application

Other: Aspiration care bundle

Interventions

Aspiration care bundle OTHER

Evidence-based aspiration care protocol

Conrol group

Eligibility Criteria

• Age: 18 Years+
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients admitted to the pulmonary intensive care unit
• Aged 18 years or older
• Connected to mechanical ventilation via ETT/TT
• Glasgow Coma Scale score: 8 or higher
• Remaining in the intensive care unit for at least 24 hours
• Patients who have not previously been diagnosed with ventilator-associated pneumonia will be included in the study.

You may not qualify if:

• Transferred from the pulmonary intensive care unit to another clinic
• Diagnosed with ventilator-associated pneumonia within the first 24 hours
• Glasgow Coma Scale score fell below 8 during the study
• Deceased at the time of data collection
• Patients who developed any complications related to aspiration (atelectasis, hypoxemia, bradypnea, etc.) prior to the study will be excluded from the study.

Sponsors & Collaborators

• Akdeniz University: lead

MeSH Terms

Conditions

Pneumonia, Ventilator-Associated

Condition Hierarchy (Ancestors)

Healthcare-Associated Pneumonia; Cross Infection; Infections; Pneumonia; Respiratory Tract Infections; Lung Diseases; Respiratory Tract Diseases; Iatrogenic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assoc. Prof. Banu Terzi

Model Details: A quasi-experimental study

Study Record Dates

• First Submitted: August 8, 2025
• First Posted: August 24, 2025
• Study Start: September 15, 2025
• Primary Completion (Estimated): June 15, 2026
• Study Completion (Estimated): September 15, 2026
• Last Updated: August 29, 2025

Record last verified: 2025-08

Data Sharing

• IPD Sharing: Will not share